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| Trade names | Telazol (in combination withtiletamine) |
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| ECHA InfoCard | 100.118.306 |
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| Formula | C15H15FN4O |
| Molar mass | 286.310 g·mol−1 |
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Zolazepam[3] (Flupyrazapon) is a pyrazolodiazepinone derivative structurally related to thebenzodiazepine drugs, which is used as ananaesthetic for a wide range of animals inveterinary medicine. Zolazepam is usually administered in combination with other drugs such as theNMDAantagonisttiletamine or the α2adrenergic receptoragonistxylazine, depending on what purpose it is being used for. It has 5-10 times the potency of diazepam.[4]
Zolazepam was developed by Horace A. de Wald and Donald E. Butler forParke-Davis[5] and was the result of a very detailed analysis of the benzodiazepine structure (U.S. patent 3,558,605 filed in 1969).
Zolazepam, in combination withtiletamine, has been used in the tranquilization of wild animals, such as gorillas and polar bears, and has been found to be superior toketamine because of reduced side-effects.[6][7] A 1:1 mixture of zolazepam and tiletamine is sold under the names Telazol and Zoletil.
