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ZNF259

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
ZPR1
Identifiers
AliasesZPR1, ZNF259, ZPR1 zinc finger, GKAF
External IDsOMIM:603901;MGI:1330262;HomoloGene:2900;GeneCards:ZPR1;OMA:ZPR1 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for ZPR1
Genomic location for ZPR1
Band11q23.3Start116,773,799bp[1]
End116,788,039bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for ZPR1
Genomic location for ZPR1
Band9|9 A5.2Start46,184,362bp[2]
End46,193,941bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ganglionic eminence

  • right testis

  • sperm

  • left testis

  • islet of Langerhans

  • sural nerve

  • Achilles tendon

  • body of pancreas

  • right lobe of liver

  • smooth muscle tissue
Top expressed in
  • epiblast

  • tail of embryo

  • embryo

  • Rostral migratory stream

  • embryo

  • seminiferous tubule

  • genital tubercle

  • muscle of thigh

  • yolk sac

  • morula
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8882

22687

Ensembl

ENSG00000109917

ENSMUSG00000032078

UniProt

O75312

Q62384

RefSeq (mRNA)

NM_003904
NM_001317086

NM_011752

RefSeq (protein)

NP_001304015
NP_003895

NP_035882

Location (UCSC)Chr 11: 116.77 – 116.79 MbChr 9: 46.18 – 46.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein ZPR1 is aprotein that in humans is encoded by theZNF259gene.[5][6][7]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000109917 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000032078 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Galcheva-Gargova Z, Konstantinov KN, Wu IH, Klier FG, Barrett T, Davis RJ (June 1996). "Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor".Science.272 (5269):1797–802.Bibcode:1996Sci...272.1797G.doi:10.1126/science.272.5269.1797.PMID 8650580.S2CID 6851783.
  6. ^Galcheva-Gargova Z, Gangwani L, Konstantinov KN, Mikrut M, Theroux SJ, Enoch T, Davis RJ (October 1998)."The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells".Molecular Biology of the Cell.9 (10):2963–71.doi:10.1091/mbc.9.10.2963.PMC 25573.PMID 9763455.
  7. ^"Entrez Gene: ZNF259 zinc finger protein 259".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

(1) Basic domains
(1.1) Basicleucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3)bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2)Zinc finger DNA-binding domains
(2.1)Nuclear receptor(Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3.1)Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3)Fork head /winged helix
(3.4)Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4)β-Scaffold factors with minor groove contacts
(4.1)Rel homology region
(4.2)STAT
(4.3) p53-like
(4.4)MADS box
(4.6)TATA-binding proteins
(4.7)High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3)Pocket domain
(0.5)AP-2/EREBP-related factors
(0.6) Miscellaneous
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