Protein-coding gene in the species Homo sapiens
Zinc finger protein 19 is aprotein that in humans is encoded by theZNF19 gene .[ 3] [ 4] [ 5]
The protein encoded by this gene contains azinc finger , anucleic acid-binding domain present in manytranscription factors . This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, onchromosome 16 .[ 5]
^a b c GRCh38: Ensembl release 89: ENSG00000157429 –Ensembl , May 2017^ "Human PubMed Reference:" .National Center for Biotechnology Information, U.S. National Library of Medicine .^ Lichter P, Bray P, Ried T, Dawid IB, Ward DC (Sep 1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes".Genomics .13 (4):999– 1007.doi :10.1016/0888-7543(92)90013-I .PMID 1505991 . ^ Bray P, Lichter P, Thiesen HJ, Ward DC, Dawid IB (Dec 1991)."Characterization and mapping of human genes encoding zinc finger proteins" .Proc Natl Acad Sci U S A .88 (21):9563– 7.Bibcode :1991PNAS...88.9563B .doi :10.1073/pnas.88.21.9563 .PMC 52758 .PMID 1946370 . ^a b "Entrez Gene: ZNF19 zinc finger protein 19" .Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells".New Biol .2 (4):363– 74.PMID 2288909 . Tommerup N, Vissing H (1995). "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders".Genomics .27 (2):259– 64.doi :10.1006/geno.1995.1040 .PMID 7557990 . Bonaldo MF, Lennon G, Soares MB (1997)."Normalization and subtraction: two approaches to facilitate gene discovery" .Genome Res .6 (9):791– 806.doi :10.1101/gr.6.9.791 .PMID 8889548 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003)."Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" .Proc. Natl. Acad. Sci. U.S.A .99 (26):16899– 903.Bibcode :2002PNAS...9916899M .doi :10.1073/pnas.242603899 .PMC 139241 .PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004)."Complete sequencing and characterization of 21,243 full-length human cDNAs" .Nat. Genet .36 (1):40– 5.doi :10.1038/ng1285 .PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004)."The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" .Genome Res .14 (10B):2121– 7.doi :10.1101/gr.2596504 .PMC 528928 .PMID 15489334 . Kimura K, Wakamatsu A, Suzuki Y, et al. (2006)."Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" .Genome Res .16 (1):55– 65.doi :10.1101/gr.4039406 .PMC 1356129 .PMID 16344560 . This article incorporates text from theUnited States National Library of Medicine , which is in thepublic domain .
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group C bHLH-PAS Group D Group E Group F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4)β-Scaffold factors with minor groove contacts
(0) Other transcription factors