In August 2022, theShmyhal Government authorized Svyrydenko to head the Interagency Working Group on the Implementation of the State Sanctions Policy.[10] She negotiated with other countries to strengthensanctions againstRussia, in particular with representatives of theUnited Kingdom.[11]
On 14 July 2025, President Zelenskyy announced a government reshuffle and nominated Svyrydenko asPrime Minister of Ukraine.[12] Her appointment was approved by the Verkhovna Rada on 17 July.[3] Svyrydenko is the second female Prime Minister of Ukraine sinceUkrainian independence in 1991, following inYulia Tymoshenko's footsteps.[1]
In 2024, Svyrydenko reported earningUAH 3,102,506 for her work at theKyiv School of Economics (KSE).[13] KSE presidentTymofiy Mylovanov confirmed that she receives approximately $6,000 per month for her teaching duties.[14] Mylovanov, in turn, is a member of the Supervisory Board of NNEGCEnergoatom, appointed by the Cabinet of Ministers when Svyrydenko wasMinister of Economy.[15] Some media and MPs (notablyVolodymyr Ariev) have raised concerns about a potential conflict of interest, pointing out that KSE-affiliated structures implemented grant programmes in which the Ministry of Economy (led by Svyrydenko) was a beneficiary.[16]
According to an investigation piece by the Ukrainian online newspaperUkrainska Pravda published in July 2024 Svyrydenko only achieved minor achievements during her time at the Economy Ministry (including small-business grant programmes and work tied toEU "Ukraine Facility" support) and on the other hand had received major criticisms from unmanned officials about project outcomes and leadership style. The same reporting described her close working relationship with theOffice of the President and thefirst lady (Olena Zelenska) during official travel; the article presented these as part of the political context around her prospective promotion at the time.[17] In the same article the authors claimed that mid-2024, President Zelenskyy repeatedly discussed with Svyrydenko the possibility of her succeedingDenys Shmyhal as prime minister. The outlet reported mixed views within the governing camp about her readiness to lead the cabinet, noting both supporters who emphasized her proximity to the president's office and critics who questioned whether she could command the entire system.[17]
Then-U.S. Secretary of Commerce Gina Raimondo included Svyrydenko's profile in the novelTime magazine'sTIME100 Next, where she was described as "emblematic of the Ukrainian people's resilience" (referring to theRussian invasion of Ukraine).[19]