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Xanthosine triphosphate

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Xanthosine triphosphate
Names

IUPAC name [(2R,3S,4R)-5-(2,6-dioxo-3H-purin-9-yl)-3,4-dihydroxy-2-tetrahydrofuranyl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
Identifiers
CAS Number	6253-56-1^N
3D model (JSmol)	Interactive image
ChemSpider	19980202^Y
PubChem CID	121887
CompTox Dashboard(EPA)	DTXSID30978122
InChI InChI=1S/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;31-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1^Y Key: BKBQKVXTMZOVRH-CYCLDIHTSA-N^Y InChI=1/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;31-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1 Key: BKBQKVXTMZOVRH-CYCLDIHTBT
SMILES OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.O=C3Nc2c(ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)N3
Properties
Chemical formula	C₁₀H₁₅N₄O₁₅P₃
Molar mass	524.17 g/mol
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Chemical compound

Xanthosine 5'-triphosphate (XTP) is anucleotide that is not produced by - and has no known function in - living cells. Uses of XTP are, in general, limited to experimental procedures on enzymes that bind other nucleotides. Deamination of purine bases can result in accumulation of such nucleotides asITP,dITP, XTP, anddXTP.^[1]

References

[edit]

^Davies O, Mendes P, Smallbone K, Malys N (2012)."Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism".BMB Reports.45 (4):259–64.doi:10.5483/BMBRep.2012.45.4.259.PMID 22531138.

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References

See also