Wingless-type MMTV integration site family, member 2, also known asWNT2, is a humangene.[5][6]
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in theWnt signaling pathway. These proteins have been implicated inoncogenesis and in several developmental processes, including regulation of cell fate and patterning duringembryogenesis. Alternatively spliced transcript variants have been identified for this gene.[5]
Li J, Nguyen L, Gleason C, et al. (2004). "Lack of evidence for an association between WNT2 and RELN polymorphisms and autism".Am. J. Med. Genet. B Neuropsychiatr. Genet.126B (1):51–7.doi:10.1002/ajmg.b.20122.PMID15048648.S2CID19378694.
Liu ZL, Li Y, Kong QY, et al. (2008). "Immunohistochemical profiling of Wnt, NF-kappaB, Stat3 and Notch signaling in human epidermal tumors".J. Dermatol. Sci.52 (2):133–6.doi:10.1016/j.jdermsci.2008.06.011.PMID18703315.
Han JC, Zhang KL, Chen XY, et al. (2007). "Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kappaB and Stat3 signaling".APMIS.115 (12):1331–43.doi:10.1111/j.1600-0643.2007.00695.x.PMID18184402.S2CID42263784.
Cheng XX, Wang ZC, Chen XY, et al. (2005). "Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin".Clin. Exp. Metastasis.22 (1):85–93.doi:10.1007/s10585-005-4578-8.PMID16132582.S2CID20775755.
Cheng XX, Wang ZC, Chen XY, et al. (2005). "Correlation of Wnt-2 expression and beta-catenin intracellular accumulation in Chinese gastric cancers: relevance with tumour dissemination".Cancer Lett.223 (2):339–47.doi:10.1016/j.canlet.2004.11.013.PMID15896469.
Ma XR, Edmund Sim UH, Pauline B, et al. (2008). "Overexpression of WNT2 and TSG101 genes in colorectal carcinoma".Tropical Biomedicine.25 (1):46–57.PMID18600204.
