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| Names | |||
|---|---|---|---|
| Preferred IUPAC name 2-Methylnaphthalene-1,4-diol | |||
| Other names 2-Methyl-1,4-naphthalenediol; 2-Methyl-1,4-dihydroxynaphthalene | |||
| Identifiers | |||
3D model (JSmol) | |||
| ChemSpider | |||
| ECHA InfoCard | 100.006.886 | ||
| UNII | |||
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| Properties | |||
| C11H10O2 | |||
| Molar mass | 174.199 g·mol−1 | ||
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |||
Menadiol is an organic compound with the formula C6H4(COH)2(CH)(CH3). It is formally a derivative of p-hydroquinone. The namevitamin K4 can refer to:
Menadiol sodium diphosphate is approved in the UK for treatment and prevention of haemorrhage, mainly in obstructive jaundice (before and after surgery).[6] Unlike natural, lipophilic forms of vitamin K, menadiol sodium diphosphate does not requirebile for absorption, hence the use in obstructive jaundice. A disadvantage is that it takes 24 hours to show effects, though the effects do last for several days. It can causehemolytic anemia, more commonly in people withglucose 6-phosphate dehydrogenase deficiency[7] orvitamin E deficiency.[6]
Menadiol is probably naturally produced by reduction ofmenadione ("vitamin K3"; seeQuinone § Reduction) as an intermediate in the conversion from K3 toMK-4.[8] It can be oxidized in experimental conditions back to menadione.[9]
