Virginia Madsen was born in Chicago, Illinois,[3] the daughter ofElaine (née Nelson), who became anEmmy Award-winning filmmaker and author, and Calvin Christian Madsen, afirefighter.[4] After Madsen's parents divorced in the late 1960s, when the children were young, her mother left a career in finance to pursue a career in the arts, encouraged by film criticRoger Ebert.[5] Madsen's siblings are actorMichael Madsen (1957–2025) and Cheryl Madsen, an entrepreneur. Her paternal grandparents were Danish, and her mother has Irish and Scottish along with distant Native American ancestry.[6] Madsen and her best friendRusty Schwimmer are graduates ofNew Trier High School inWinnetka, Illinois.[7]
Madsen later attended the Ted Liss Acting Studio in Chicago, and Harand Camp Adult Theater Seminar inElkhart Lake, Wisconsin. Of her experience with Liss, she said: "I had wanted to join his class since I was 12. It was well worth the wait because I don't think I could have got that sort of training anywhere else, especially in the United States ... I always wanted to make a real career out of acting."[8]
Madsen made her acting debut at age 22, in abit part where she landed her role as Lisa in the romantic comedy filmClass (1983), co-starringJacqueline Bisset andRob Lowe. She next appeared inKenny Loggins' music video for "I'm Free (Heaven Helps the Man)" from theFootloose (1984) soundtrack.
Madsen first became known to audiences in 1986 with her portrayal of a Catholic school girl who fell in love with a boy from a prison camp in Duncan Gibbons'Fire with Fire, though the film drew scathing reviews. As beauty queen Dixie Lee Boxx, she was the love interest of minor league baseball manager Cecil "Stud" Cantrell (William Petersen) in theHBO original filmLong Gone (1987). That same year she also appeared in the music video for "I Found Someone" byCher. She played a secretary named Allison Rowe in the comedy filmHot to Trot (1988).
She also starred asHelen Lyle, an anthropology student, in the horror filmCandyman (1992), which drew good reviews and was a box office success.
She appeared in a small role in theFrancis Ford Coppola dramaThe Rainmaker (1997) alongsideMatt Damon andClaire Danes. Film criticRoger Ebert said that Madsen had a "strong scene",[11] while reviewer James Berardinelli noted that "the supporting cast is solid, with turns from . . . Virginia Madsen as a witness for the plaintiff".[12]
Madsen delivered a critically acclaimed performance inSideways (2004), directed byAlexander Payne. Her role catapulted her onto the HollywoodA-list.[13]
In 1988, Madsen appeared as Maddie Hayes' cousin in the fifth and final season of theABC drama seriesMoonlighting. She has since made various television appearances, includingStar Trek: Voyager,CSI: Miami,Dawson's Creek,The Practice,Frasier, and other television series. She was also co-host of the long-running television seriesUnsolved Mysteries in 1999, during the show's eleventh season (which was also the second and final season onCBS). She starred alongsideRay Liotta in the short-lived CBS crime drama seriesSmith. She also had a recurring role in theeighth and final season in theUSA Network comedy-drama seriesMonk.
In 2010, she landed the starring role of Cheryl West in the ABC comedy-drama seriesScoundrels. In December 2010, it was announced that she would be joining the cast of theNBC science fiction seriesThe Event.[14] In 2012, she joined the cast of theAMC western drama seriesHell on Wheels as Mrs. Hannah Durant, first appearing in episode eight of season 2, "The Lord's Day". In 2013, Madsen began appearing onLifetime'sWitches of East End as Penelope Gardiner, the main villainess of the first season.
In 2008, Madsen formed her own film production company called Title IX Productions.[16] Her first project was a film made with her mother titledI Know a Woman Like That. The film is a documentary about the lives of older women. On the creation of the film, she said her mother's active lifestyle was an inspiration to start filming.
My mother's level of activity, of productivity, was exactly why I thought a project like this would work. Originally, when we put the idea together, she had said, "I'm far too busy. I'm going to Holland, and then I'm going here and there and I'm writing my book." But that's really what it's about.[17]
Madsen was married to actor and directorDanny Huston after meeting on the set ofMr. North (1988). They married in 1989 and divorced in 1992.[18] From 1993 to 1998, Madsen was in a partnership relationship withAntonio Sabàto Jr., with whom she had one son.[19] In 2020, Madsen married actor Nick Holmes after dating for over ten years.[20]
^Madsen's opening monologue fromDune ("In this time, the most precious substance in the universe is the spice, melange. The spice extends life. The spice expands consciousness.") was later sampled byIsrael-based groupAstral Projection in their tracks "Dancing Galaxy" and "Ambient Galaxy" on their albumDancing Galaxy, and bydrum and bass artistAphrodite in his song "Spice (Even Spicier)".
^Ebert, Roger (November 21, 1997)."The Rainmaker".RogerEbert.com. RetrievedNovember 19, 2017.
^Berardinelli, James (1997)."The Rainmaker".ReelViews. RetrievedJune 16, 2017.
^abcdef"Virginia Madsen (visual voices guide)". Behind The Voice Actors. RetrievedApril 23, 2025. A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information.