 | |
| Names | |
|---|---|
| IUPAC name 2-(4-Cyclohexyl-1-naphthyl)propanoic acid | |
| Other names Quadrisol | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.068.339 |
| UNII | |
| |
| |
| Properties | |
| C19H22O2 | |
| Molar mass | 282.383 g·mol−1 |
| Pharmacology | |
| QM01AE90 (WHO) | |
| Legal status | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Vedaprofen is anonsteroidal anti-inflammatory drug (NSAID) used inveterinary medicine for the treatment of pain and inflammation due to musculoskeletal disorders in dogs and horses and for the treatment of pain due tohorse colic.[4] It is a member of theprofen drug class.
Vedaprofen isindicated for the reduction of inflammation and relief of pain associated with musculo-skeletal disorders and soft tissue lesions (traumatic injuries and surgical trauma).[1][2]
Vedaprofen can be synthesized beginning with 1-cyclohexylnaphthylene (left).[5][6] Chloromethylation followed by functional group interconversion provides the ester (center right).Alkylation withmethyl iodide then gives vedaprofen (right).
Vedaprofen was approved for veterinary use in the European Union in April 1997.[1][2]
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;†withdrawn drugs;‡veterinary use. | |
