Greenville–Spartanburg Metropolitan Area | |
|---|---|
| Greenville–Spartanburg–Anderson, SC Combined Statistical Area | |
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| Country | |
| State | |
| Principal cities | |
| Area | |
• Total | 6,168 sq mi (15,980 km2) |
| • Land | 6,008 sq mi (15,560 km2) |
| • Water | 141 sq mi (370 km2) 2.2% |
| Population (2020) | |
| • CSA | 1,487,610[1](39th) |
| GDP | |
| • MSA | $57.403 billion (2022) |
| • CSA | $76.888 billion (2022) |
| Time zone | UTC−5 (EST) |
| • Summer (DST) | UTC−4 (EDT) |
| Area codes | 864 and 821 |
The Upstate, historically known asthe Upcountry,[4] is a region of the U.S. state ofSouth Carolina, comprising the northwesternmost area of the state. Although loosely defined among locals, the general definition includes the 10 counties of the commerce-richI-85 corridor in the northwest corner of South Carolina. This definition coincided with the Greenville-Spartanburg-Anderson, SCCombined Statistical Area, as first defined by the Office of Management and Budget (OMB) in 2015. In 2023, the OMB issued its most updated definition of the CSA that coincides again with the 10-county region.[5]
The region's population was 1,487,610 as of 2020. Situated betweenAtlanta andCharlotte, the Upstate is the geographical center of theCharlanta megaregion. AfterBMW's initial investment, foreign companies, including others from Germany, have a substantial presence in the Upstate; several large corporations have established regional, national, or continental headquarters in the area.Greenville is the largest city in the region; it has a population of 72,227 and an urban-area population of 387,271, and it is the base of most commercial activity. Greer andSpartanburg are next in population.
Ten counties are included in the Upstate of South Carolina:Greenville,Spartanburg,Anderson,Pickens,Oconee,Greenwood,Laurens,Cherokee,Union,Abbeville.
| County | 2023 Estimate | 2020 Census | Change |
|---|---|---|---|
| Greenville County | 558,036 | 525,534 | +6.18% |
| Spartanburg County | 356,698 | 327,997 | +8.75% |
| Anderson County | 213,076 | 203,718 | +4.59% |
| Pickens County | 135,495 | 131,404 | +3.11% |
| Oconee County | 81,221 | 78,607 | +3.33% |
| Greenwood County | 69,460 | 69,351 | +0.16% |
| Laurens County | 68,873 | 67,539 | +1.98% |
| Cherokee County | 56,714 | 56,216 | +0.89% |
| Union County | 26,629 | 27,244 | −2.26% |
| Abbeville County | 24,434 | 24,295 | +0.57% |
| Total | 1,590,636 | 1,511,905 | +5.21% |
As of 2023, the Greenville–Spartanburg–Anderson CSA includes all ten counties in the Upstate. Within the CSA are a total of twometropolitan statistical areas and threemicropolitan statistical areas.[5]
As of the 2020 Census, the Greenville–Spartanburg–Anderson CSA had a population of 1,511,105.
| MSA | County | Population (2020)[6] |
|---|---|---|
| Greenville–Anderson | Greenville,Anderson,Pickens,Laurens | 928,195 |
| Spartanburg | Spartanburg,Union | 355,241 |
| Total: | 1,283,436 |
| μSA | County | Population (2020)[7] |
|---|---|---|
| Seneca | Oconee | 78,607 |
| Greenwood | Greenwood,Abbeville | 93,646 |
| Gaffney | Cherokee | 56,216 |
| Total: | 228,469 |
The following population rankings are based on the 2010 Census.[8]
Greenville,Spartanburg,Anderson,Greer,Mauldin, andGreenwood,
The OMB labels all these cities asprincipal cities in their respective MSAs and μSA.[5]
Cities:Easley,Simpsonville
CDPs:Taylors,Wade Hampton
Cities:Clemson,Gaffney, andFountain Inn, South Carolina.
Gaffney is a principal city in its μSA. If students fromClemson University are included, Clemson has close to 30,000 residents.
CDP's:Berea,Five Forks,Gantt,Parker,Boiling Springs
Communities in the Upstate with under 10,000 residents include:
Cities:
Towns:
Seneca is a principal city in its μSA. According to the 2010 Census, no town in the Upstate has a population greater than 6000.
CDPs:

The following table shows the major institutions of higher education in the Upstate.
In 2008,U.S. News ranked Furman as the 37th-best liberal arts college, Wofford College as the 59th-best, and Presbyterian College as the 101st-best.[citation needed] Also, they ranked Clemson University as the 67th-best national university.[citation needed] According to the Bob Jones University, its Museum and Gallery constitutes the largest collection of religious art in the Western Hemisphere.[9]
The majority of business and commerce in the Upstate takes place in Greenville County. Greenville has the largest concentration of businesses and financial institutions in its downtown area. In fact, the Greenville-Spartanburg-Anderson MSA was ranked seventh in the nation by site consultants considering the top markets for economic development. Many financial institutions have regional offices located indowntown Greenville. These includeBank of America and the now-defunctWachovia. Other major industries of commerce in the Upstate include the auto industry, which is concentrated mainly along the corridor between Greenville and Spartanburg around the BMW manufacturing facility in Greer.
The other major industry in the Upstate is the healthcare and pharmaceuticals. Greenville Hospital System and Bon Secours St. Francis Health System are the area's largest in the healthcare sector, while the pharmaceutical corporation ofBausch & Lomb has set up regional operations alongside smaller recently developed local companies such as IRIX Manufacturing and Pharmaceutical Associates. The Upstate is also home to a large amount of private-sector and university-based research activity, including R&D facilities for Michelin, Fuji, and GE Vernova and research centers to support the automotive, life sciences, plastics, and photonics industries.Clemson University, BMW,IBM,Microsoft, andMichelin have combined their resources to createClemson University International Center for Automotive Research, a research park that specializes in the development of automotive technology.
These corporations have a major presence in the Upstate:Adidas,Advance America,Bank of America,BMW of North America,Bon Secours St. Francis Health SystemBon Secours | Bringing Health Care and Good Help to Those in Need,Bosch North America,Denny's Restaurants,Dunlop Sport,Ernst & Young,Fluor Corporation,Freightliner,GE Vernova,Prisma Health[1],IBM,Kemet Corporation,Liberty Corporation,Spartanburg Regional Healthcare System,Michelin of North America,Microsoft,Milliken & Company,Spartanburg Regional Health System,Spectrum Communications,SunTrust,Ovation Brands,Perrigo Company of South Carolina,Techtronic Industries,Toronto-Dominion Bank,United Community andVerizon.
• BMW's only North American manufacturing plant is located in Spartanburg County, with an investment of $3.7 billion.[10]
•Fujifilm located their first manufacturing facility in the U.S. in Greenwood County.[11]
• Michelin North America's headquarters is located in Greenville, along with seven manufacturing plants, R&D facility, and test track located in the Upstate. Michelin employs more than 7,800 in South Carolina.[12]
• Walgreens has their southeastern distribution center located in Anderson County, which employs mentally disabled workers as nearly 40% of their workforce.[13]

The Upstate is served by two major interstate highways,I-85 andI-26. Other major interstate spurs includeI-185,I-385, andI-585. The major airport in the region isGreenville-Spartanburg International Airport, located nearly halfway between Greenville and Spartanburg in suburban Greer. Greenville, Spartanburg, Anderson, Clemson, Pickens, Union, and Gaffney each have smaller airfields.Amtrak service along theCrescent Line stops in Spartanburg, Greenville, and Clemson.
The Upstate region is served by three regional newspapers:The Greenville News, the (Spartanburg)Herald-Journal, and theAnderson Independent-Mail, each of which serves its individual city and surrounding area.The Post and Courier recently opened expansion newsrooms in Greenville and Spartanburg for coverage of the Upstate, including Clemson.
The Upstate is part of the vastly larger Greenville-Spartanburg-Anderson-Ashevilledesignated market area, which extends intowestern North Carolina and northeasternGeorgia. These television stations serve the region: