 | |
| Names | |
|---|---|
| Preferred IUPAC name 6-Methyl-2-(4-methylanilino)-4H-3,1-benzoxazin-4-one | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider |
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| ECHA InfoCard | 100.236.075 |
| UNII | |
| |
| |
| Properties | |
| C16H14N2O2 | |
| Molar mass | 266.300 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
URB754 was originally reported by Piomelliet al. to be a potent, noncompetitiveinhibitor ofmonoacylglycerol lipase (MGL).[1] However, recent studies have shown that URB754 failed to inhibit recombinant MGL, and brainFAAH activity was also resistant to URB754.[2] In a later study by Piomelliet al., the MGL-inhibitory activity attributed to URB754 is in fact due to a chemical impurity present in the commercial sample, identified as bis(methylthio)mercurane.[3]
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