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UBE2E2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
UBE2E2
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

1Y6L

Identifiers
AliasesUBE2E2, UBCH8, ubiquitin conjugating enzyme E2 E2
External IDsOMIM:602163;MGI:2384997;HomoloGene:77337;GeneCards:UBE2E2;OMA:UBE2E2 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for UBE2E2
Genomic location for UBE2E2
Band3p24.3Start23,203,020bp[1]
End23,591,794bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for UBE2E2
Genomic location for UBE2E2
Band14|14 A1Start3,575,429bp[2]
End3,896,121bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • prefrontal cortex

  • popliteal artery

  • tibial arteries

  • Brodmann area 9

  • germinal epithelium

  • myocardium of left ventricle

  • cingulate gyrus

  • anterior cingulate cortex

  • right coronary artery
Top expressed in
  • dentate gyrus of hippocampal formation granule cell

  • motor neuron

  • Region I of hippocampus proper

  • hippocampus proper

  • fossa

  • visual cortex

  • barrel cortex

  • primary visual cortex

  • condyle

  • trigeminal ganglion
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

7325

218793

Ensembl

ENSG00000182247

ENSMUSG00000058317

UniProt

Q96LR5

Q91W82

RefSeq (mRNA)

NM_152653
NM_001370225
NM_001370226
NM_001370227
NM_001370228

NM_144839
NM_001360327
NM_001360328

RefSeq (protein)

NP_689866
NP_001357154
NP_001357155
NP_001357156
NP_001357157

NP_659088
NP_001347256
NP_001347257

Location (UCSC)Chr 3: 23.2 – 23.59 MbChr 14: 3.58 – 3.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ubiquitin-conjugating enzyme E2 E2 is aprotein that in humans is encoded by theUBE2E2gene.[5][6]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000182247Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000058317Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Kimura M, Hattori T, Matsuda Y, Yoshioka T, Sumi N, Umeda Y, Nakashima S, Okano Y (Dec 1997). "cDNA cloning, characterization, and chromosome mapping of UBE2E2 encoding a human ubiquitin-conjugating E2 enzyme".Cytogenet Cell Genet.78 (2):107–11.doi:10.1159/000134639.PMID 9371400.
  6. ^"Entrez Gene: UBE2E2 ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)".

Further reading

[edit]

External links

[edit]
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Ubiquitin-conjugating enzyme E2 E2
PDB gallery
  • 1y6l: Human ubiquitin conjugating enzyme E2E2
    1y6l: Human ubiquitin conjugating enzyme E2E2
Chaperones/
protein folding
Heat shock proteins/
Chaperonins
Other
Protein targeting
Ubiquitin
(ubiquitylation)
Ubiquitin-like proteins
(UBL)
SUMO protein
(SUMOylation)
  • E2 SUMO-conjugating enzyme
Other


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