U.S. Route 45
Route information
Maintained byKYTC
Length	51.880 mi[1] (83.493 km)
Major junctions
South end	US 45 /SR 3 atTennessee state line inFulton
Major intersections	US 45 Byp. inMayfield I-69 near Mayfield I-24 inPaducah US 62 /KY 731 in Paducah US 60 in Paducah US 45 Bus. in Paducah I-24 BL /US 60 Bus. in Paducah
North end	US 45 atOhio River in Paducah
Location
Country	United States
State	Kentucky
Counties	Fulton,Hickman,Graves,McCracken
Highway system
United States Numbered Highway System List Special Divided Kentucky State Highway System Interstate US State Parkways
←KY 44 →KY 46

U.S. Route 45 (US 45) enters Kentucky atFulton inFulton County and travels northeast throughHickman County,Graves County, andMcCracken County. After passing throughMayfield in Graves County it heads directly north intoPaducah as a four-lane highway. In Paducah, US 45 serves as a major artery, intersecting withInterstate 24 at Exit 7, and intersectingUS 60 and62. U.S. 45 leaves Kentucky from Paducah's northern border across the two-lane, metal-grateBrookport Bridge toBrookport, Illinois across theOhio River.

US 45 enters Kentucky at Fulton in Fulton County where it travels around the west side and then north side of town before entering Hickman County. It travels just to the south and east ofI-69 as it passes briefly through Hickman County and into Graves County. In Graves County US 45 travels northeast and passes through the communities ofWater Valley andWingo. Roughly 7 miles (11 km) northeast of Wingo, US 45 passes through Mayfield where it forms an intersection with US 45 Bypass before passing through the heart of town. Just north of town, US 45 intersects US 45 Bypass and Purchase Parkway and becomes a four-lane divided highway as it turns toward the north. US 45 continues northward through rural sections of Graves County and into McCracken County. The previous routing between these two points is now designated Kentucky Route 1241. In McCracken County, US 45 passes throughLone Oak and then passes underI-24 as it enters Paducah. In Paducah, US 45 forms intersections withUS 60,US 62, US 60 Business, I-24 Business, and US 45 Business as it passes through the western part of town. US 45 crosses the Ohio River via theBrookport Bridge into Illinois 51.880 miles (83.493 km) from the Tennessee state line.^[2]

US 45 was signed in Kentucky by 1928, although it was not yet paved.^[3] The entire route in Kentucky was paved by 1939.^[4]

County	Location	mi	km	Destinations	Notes
Fulton	Fulton	0.000	0.000	US 45 south /KY 116 east (Highland Drive)	Continuation into Tennessee
				KY 116 west (State Line Street)	North end of KY 116 overlap (southbound only);Kentucky–Tennessee line
		0.065	0.105	KY 1648 north (Second Street)
		0.579	0.932	Redbud Lane (KY 1644 north)
		0.579	0.932	KY 1648 toI-69 /US 51 –Clinton
		1.345	2.165	KY 1718 north (Fairview Avenue) – Business District
		1.790	2.881	KY 307 south (M.L. King Jr. Drive) – Business District	South end of KY 307 overlap
		1.845	2.969	KY 307 north toI-69 /US 51	North end of KY 307 overlap
Hickman	​	3.439	5.535	KY 1218
	​	3.846	6.190	KY 2569
	​	5.162	8.307	KY 94 west	South end of KY 94 overlap
Graves	Water Valley	6.670	10.734	KY 94 east /KY 1529 west –Murray	North end of KY 94 overlap
		7.012	11.285	KY 1283 north
		7.118	11.455	ToKY 2422 / Hubbard Street (KY 1839) –Camp Beauregard
	​	13.122	21.118	KY 944 west
	Wingo	13.668	21.997	KY 1806 north (Whitnell Drive)
		13.963	22.471	KY 339 south –Sedalia, Business District	South end of KY 339 overlap
		14.043	22.600	KY 339 north toI-69 –Clinton	North end of KY 339 overlap
	​	16.916	27.224	KY 58 west –Clinton	South end of KY 58 overlap
	Pryorsburg	17.572	28.279	KY 1748
	​	21.184	34.092	US 45 Byp. north toI-69 –Paducah	Interchange
	Mayfield	23.719	38.172	KY 58 east /KY 80 Bus. west (Broadway)	North end of KY 58 overlap
		24.697	39.746	KY 121 –Wickliffe,Cairo,Murray
		24.833	39.965	KY 3141 east (Crittendon Lane)
	​	25.563	41.140	I-69 /US 45 Byp. south –Fulton,Benton	I-69 exit 25
	​	25.833	41.574	KY 1830 west
	​	27.055	43.541	KY 1276 west (Key Bottom Road)
	​	27.289	43.917	KY 1241 north
	Hickory	29.082	46.803	Powell Road (KY 3043 west)
	​	30.743	49.476	KY 2194 (Doyle Road)
	​	31.861	51.275	KY 408 –Viola
	​	33.475	53.873	KY 849 –Lowes,Folsomdale
	​	34.427	55.405	KY 1241
McCracken	​	38.347	61.714	KY 1241 –Melber
	​	40.672	65.455	KY 1288 east (Lebanon Church Road)
	​	41.695	67.102	KY 999 east (Krebs Station Road)
	​	43.865	70.594	KY 1241 south
	​	44.215	71.157	KY 339 south (Clinton Road) –Melber
	Lone Oak	44.413	71.476	KY 1322 west (Lovelaceville Road)
		44.779	72.065	KY 1286 (Friendship Road)
	​	45.447	73.140	KY 3074 east (Bleich Road)
	Paducah	46.098	74.188	I-24 toUS 62 –St. Louis,Nashville	I-24 exit 7
		46.976	75.601	KY 1310 east (Berger Road)
		47.304	76.128	US 62 west (Alben Barkley Drive) /KY 731 north (Lone Oak Road) toI-24 west –Bardwell,Wickliffe	South end of US 62 overlap
		47.950	77.168	US 60 east /US 62 east (Jackson Street)	North end of US 62 overlap; south end of US 60 overlap
		48.197	77.566	US 45 Bus. north (Washington Street)
		48.886	78.674	US 60 west (Joe Clifton Drive) –Barkley Airport	North end of US 60 overlap
		49.132	79.070	I-24 BL /US 60 Bus. (Park Avenue) –Barkley Airport
		49.796	80.139	KY 305 (Cairo Road)
		50.186	80.767	US 45 Bus. south (Eighth Street)
Ohio River		51.880	83.493	Brookport Bridge;Kentucky–Illinois line
				US 45 north –Brookport	Continuation into Illinois
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

U.S. Route 45 Bypass
Location	Mayfield, Kentucky
Length	3.818 mi[1] (6.144 km)

US 45 Bypass in Mayfield begins at a junction with US 45 on the southwest side of Mayfield and forms a concurrency with I-69 at exit 21 0.958 miles (1.542 km) north of US 45. It carries this concurrency for 2.860 miles (4.603 km) and ends at a junction with US 45 at exit 25 of the parkway north of Mayfield. Since the formerPurchase Parkway has been re-designated I-69, US 45 Bypass signs have been removed from the I-69 concurrency, and the north interchange with US 45.

The entire route is inGraves County.

Location	mi[1]	km	Exit	Destinations	Notes
​	0.000	0.000		US 45 /KY 80 east –Mayfield,Fulton	Partial interchange; southern terminus; south end of KY 80 concurrency
Mayfield			21	I-69 south –Fulton	South end of I-69 overlap; I-69 Exit 21
	1.338	2.153	22	KY 80 west /KY 80 Bus. east –Fancy Farm,Mayfield	North end of KY 80 concurrency; western terminus of KY 80 Business
	2.794	4.497	24	KY 121 –Wickliffe,Mayfield
​	3.818	6.144		I-69 north /US 45 –Benton,Mayfield	Northern terminus; north end of I-69 overlap; I-69 exit 25
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

U.S. Route 45 Business
Location	Paducah, Kentucky
Length	4.378 mi[1] (7.046 km)

US 45 Business in Paducah begins at an intersection with US 45 in downtown Paducah and travels northeast through town. As it nears the Ohio River, it turns to the northwest and ends at a junction with US 45 south of the Brookport Bridge over the Ohio River 4.378 miles (7.046 km) from its origin.

The entire route is inPaducah,McCracken County.

mi	km	Destinations	Notes
0.000	0.000	US 45	Southern terminus
2.039	3.281	US 60 Bus.	South end of US 60 Business overlap
2.119	3.410	KY 3238 (Kentucky Avenue)
2.188	3.521	KY 3238 (Broadway Street)
2.946	4.741	US 60 Bus.	North end of US 60 Business overlap
4.378	7.046	US 45	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

U.S. Route 45
Previous state: Tennessee	Kentucky	Next state: Illinois

• U.S. Route 45
• U.S. Highways in Kentucky
• Transportation in Fulton County, Kentucky
• Transportation in Hickman County, Kentucky
• Transportation in Graves County, Kentucky
• Transportation in McCracken County, Kentucky

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