ATrypanosomiasis vaccine is avaccine againsttrypanosomiasis. No effective vaccine currently exists, but development of a vaccine is the subject of current research.
It has been suggested that these challenges could be overcome by a vaccine against the initialantigens,[4] or generating an immune response against thecysteine protease (for example,cruzipain).[5][6]
An effective vaccine was achieved in 2021 using a mouse model of infection withTrypanosoma vivax.[7]
^Lalmanach G, Boulangé A, Serveau C, et al. (May 2002). "Congopain from Trypanosoma congolense: drug target and vaccine candidate".Biol. Chem.383 (5):739–49.doi:10.1515/BC.2002.077.PMID12108538.S2CID22315392.
^Authié E, Boulangé A, Muteti D, Lalmanach G, Gauthier F, Musoke AJ (November 2001). "Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: targeting the disease rather than the parasite".Int. J. Parasitol.31 (13):1429–33.doi:10.1016/S0020-7519(01)00266-1.PMID11595229.
