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Tridihexethyl

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Tridihexethyl
Clinical data
ATC code
Identifiers
  • 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC21H36NO+
Molar mass318.525 g·mol−1
3D model (JSmol)
  • OC(c1ccccc1)(CC[N+](CC)(CC)CC)C2CCCCC2
  • InChI=1S/C21H36NO/c1-4-22(5-2,6-3)18-17-21(23,19-13-9-7-10-14-19)20-15-11-8-12-16-20/h7,9-10,13-14,20,23H,4-6,8,11-12,15-18H2,1-3H3/q+1 checkY
  • Key:NPRHVSBSZMAEIN-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Tridihexethyl (which is commonly used as its chloride salt, tridihexethyl chloride) is ananticholinergic,antimuscarinic andantispasmodic drug. It may be used, usually in combination with other drugs, to treat acquirednystagmus[1] orpeptic ulcer disease.[2] Many patients discontinue the drug because of unwanted side effects.

It is also known as Pathilon or Propethonum.[3]

References

[edit]
  1. ^Leigh RJ, Burnstine TH, Ruff RL, Kasmer RJ (November 1991). "Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride".Neurology.41 (11):1737–41.doi:10.1212/wnl.41.11.1737.PMID 1944902.S2CID 23270800.
  2. ^"DB00505 (Tridihexethyl)".DrugBank.
  3. ^"Tridihexethyl".Mongabay.com. Archived fromthe original on 2007-11-15.
Drugs for
functional
bowel
disorders
Antimuscarinics
Tertiary
amino group
Quaternary
ammonium

compounds
Phosphodiesterase
inhibitors
Acting on
serotonin receptors
Other
Belladonna
and derivatives
(antimuscarinics)
Propulsives
mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(andprodrugs)
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