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Reuptake modulator

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(Redirected fromTransporter modulator)

Type of pharmaceutical drug

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Areuptake modulator, ortransporter modulator, is a type ofdrug whichmodulates thereuptake of one or moreneurotransmitters via their respectiveneurotransmitter transporters. Examples of reuptake modulators includereuptake inhibitors (transporter blockers) andreuptake enhancers.

v t e Receptor/signaling modulators
Amino acids and similar/related	Amino acids and related:GABA receptor modulators GABA_A receptor positive modulators GABA metabolism and transport modulators GHB receptor modulators Glutamate metabolism and transport modulators Glycine receptor modulators Ionotropic glutamate receptor modulators Metabotropic glutamate receptor modulators Monoamines:Adrenergic receptor modulators Dopamine receptor modulators Histamine receptor modulators Melatonin receptor modulators Monoamine metabolism modulators Monoamine neurotoxins Monoamine releasing agents Monoamine reuptake inhibitors Serotonin receptor modulators hTAAR modulators Acetylcholine:Acetylcholine metabolism and transport modulators Muscarinic acetylcholine receptor modulators Nicotinic acetylcholine receptor modulators Others:Imidazoline receptor modulators Purine receptor modulators Sigma receptor modulators Thyroid hormone receptor modulators
Lipids	Eicosanoids:Cannabinoid receptor modulators Leukotriene signaling modulators Prostanoid signaling modulators Phospholipids:Lysophospholipid signaling modulators PAF receptor modulators Steroids:Androgen receptor modulators Estrogen receptor modulators Glucocorticoid receptor modulators Mineralocorticoid receptor modulators Progesterone receptor modulators Steroid metabolism modulators Other nuclear receptors:Aryl hydrocarbon receptor modulators Estrogen-related receptor modulators FXR and LXR modulators PPAR modulators Retinoid receptor modulators Vitamin D receptor modulators Xenobiotic-sensing receptor modulators
Peptides/proteins	Peptides:Angiotensin receptor modulators GH/IGF-1 axis signaling modulators GnRH and gonadotropin receptor modulators Melanocortin receptor modulators Neurokinin receptor modulators Opioid receptor modulators Oxytocin and vasopressin receptor modulators Cytokines:Cytokine receptor modulators Chemokine receptor modulators Interleukin receptor modulators TNF receptor superfamily modulators Growth factors:Growth factor receptor modulators TGFβ receptor superfamily modulators
Others and non-receptor	Enzymes:Cytochrome P450 modulators Histone deacetylase inhibitors Phosphodiesterase inhibitors Ion channels:Ion channel modulators TRP channel modulators Transporters:Sodium-glucose transporter modulators Symporter inhibitors Others:Nitric oxide signaling modulators

Pharmacomodulation

Types

♦Enzyme:Inducer
Inhibitor

♦Ion channel:Opener
Blocker

♦Transporter [Reuptake vsEfflux]:Enhancer (RE)
Inhibitor (RI)
Releaser (RA)

♦ Miscellaneous:Precursor
Cofactor

Classes

Enzyme

seeEnzyme inhibition

Ion channel

SeeIon channel modulators

Receptor &
transporter

BA/M

Adrenergic	Adrenergic receptor agonist (α β (1 2)) Adrenergic receptor antagonist (α (1 2) β) Norepinephrine reuptake inhibitor (NRI)
Dopaminergic	Dopamine receptor agonist Dopamine receptor antagonist Dopamine reuptake inhibitor (DRI)
Histaminergic	Histamine receptor agonist Histamine receptor antagonist (H₁ H₂ H₃)
Serotonergic	Serotonin receptor agonist Serotonin receptor antagonist (5-HT₃) Serotonin reuptake inhibitor (SRI)

GABAergic	GABA receptor agonist GABA receptor antagonist GABA reuptake inhibitor (GRI)
Glutamatergic	Glutamate receptor agonist (AMPA) Glutamate receptor antagonist (NMDA) Glutamate reuptake inhibitor