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| Routes of administration | By mouth |
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| ECHA InfoCard | 100.050.178 |
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| Formula | C16H24N4O2 |
| Molar mass | 304.394 g·mol−1 |
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Tracazolate (ICI-136,753) is ananxiolyticdrug which is used in scientific research. It is apyrazolopyridinederivative, most closely related topyrazolopyrimidine drugs such aszaleplon, and is one of a structurally diverse group of drugs known as thenonbenzodiazepines which act at the same receptor targets asbenzodiazepines but have distinct chemical structures.[1]
Tracazolate has primarilyanxiolytic andanticonvulsant effects, withsedative andmuscle relaxant effects only appearing at higher doses.[2] It has a unique receptor binding profile involving allosteric modulation of severalGABAA receptor subtypes, being selective for GABAA receptors containing α1 and β3 subunits, but exhibiting different effects depending on the third type of subunit making up the receptor complex.[3]
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