Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Tolgabide

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Tolgabide
Clinical data
ATC code
  • none
Legal status
Legal status
  • Investigational
Identifiers
  • 4-{[(E)-(3-Chloro-5-methyl-6-oxocyclohexa-2,4-dien-1-ylidene)(4-chlorophenyl)methyl]amino}butanamide
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC18H18Cl2N2O2
Molar mass365.25 g·mol−1
3D model (JSmol)
  • Cc1cc(cc(c1O)/C(=N/CCCC(=O)N)/c2ccc(cc2)Cl)Cl
  • InChI=1S/C18H18Cl2N2O2/c1-11-9-14(20)10-15(18(11)24)17(22-8-2-3-16(21)23)12-4-6-13(19)7-5-12/h4-7,9-10,24H,2-3,8H2,1H3,(H2,21,23)/b22-17+
  • Key:AOAFGVWKONLQRN-OQKWZONESA-N

Tolgabide (INN; development codeSL-81.0142) is adrug which was patented bySynthélabo as ananticonvulsant but was never marketed.[1] It is ananalogue ofprogabide and acts similarly to it as aprodrug ofGABA, and therefore as an indirectagonist of theGABA receptors.[1][2]

See also

[edit]

References

[edit]
  1. ^abTriggle DJ (1996).Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC.ISBN 0-412-46630-9.
  2. ^"The use of common stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances"(PDF). 2002.[dead link]
GABAergics
GABAARPAMs
GABA-T inhibitors
Others
Channel
modulators
Sodium blockers
Calcium blockers
Potassium openers
Others
CA inhibitors
Others
Ionotropic
GABAATooltip γ-Aminobutyric acid A receptor
GABAATooltip γ-Aminobutyric acid A-rho receptor
Metabotropic
GABABTooltip γ-Aminobutyric acid B receptor
Retrieved from "https://en.wikipedia.org/w/index.php?title=Tolgabide&oldid=1244806612"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp