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Tincture of cannabis, sometimes known asgreen dragon, is analcoholiccannabis concentrate. The solubility ofTHC inethanol is greater than 1 g/mL.[1]
According to theEuropean Medicines Agency (EMA) cannabis tinctures (tincturea) are a type of liquid cannabis extract obtained usingethanol,water,glycerol,propylene glycol andfatty oils as extraction solvents, depending on the type of tincture (and also on the solvent used) it can have a specific mass/volume ratio or a specifictherapeutic agents content.[2]
Cannabis tinctures are used in the production of specific extracts, likenabiximols.
Cannabis tincture appeared in theUnited States Pharmacopoeia until 1942 (Australia 1977, UK 1970s).[3]
The pharmacological target for cannabis, theendocannabinoid system, has been researched since its discovery in the 1980s.
The tincture is typically made by soaking the dried flowers of the femalehemp plant (marijuana) inethanol. Thetetrahydrocannabinol (THC) and othercannabinoidsdissolve into the alcohol. Some preparations also extract some of the water-based plant products such aschlorophyll, resulting in a dark green or brown liquid. Baking or drying the cannabis todecarboxylate prior to the alcohol bath increases the amount of THC in the resulting preparation.[4][unreliable source?][5]
The tincture is ordinarily consumed orally, but may also be applied to the skin.
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