Thomas Earl Starzl (March 11, 1926 – March 4, 2017) was an Americanphysician, researcher, and expert onorgan transplants. He performed the firsthuman liver transplants, and has often been referred to as "the father of modern transplantation".[1] A documentary, titled "Burden of Genius,"[2] covering the medical and scientific advances spearheaded by Starzl himself, was released to the public in 2017 in a series of screenings. Starzl also penned his autobiography,The Puzzle People: Memoirs Of A Transplant Surgeon, which was published in 1992.
Starzl was born on March 11, 1926, inLe Mars, Iowa, the son of newspaper editor and science fiction writerRoman Frederick Starzl and Anna Laura Fitzgerald who was a teacher and a nurse. He was the second of four siblings.[3] Originally intending to become a priest in his teenage years, Starzl changed his plans drastically when his mother died frombreast cancer in 1947.[3] He briefly served in theUnited States Navy Reserve after graduating fromLe Mars High School in 1944.
Starzl spent an extra year at medical school, using the additional time to complete a doctorate inneurophysiology, in 1952. He wrote a seminal paper describing a technique to record the electrical responses of deep brain structures to sensory stimuli such as a flash of light or a loud sound. The paper is highly cited, having been referenced in 384 articles by January 2019.[5]
After obtaining his medical degree, Starzl trained in surgery at Johns Hopkins Hospital in Baltimore and Jackson Memorial Hospital in Miami. At both places, he conducted lab and animal research, showing a keen interest in liver biology.[7]
Thomas Starzl after performing a transplant surgery circa 1990
The Institute for Scientific Information released information in 1999 that documented that his work had been cited more than any other researcher in the world. Between 1981 and June 1998, he was cited 26,456 times.[3]
His autobiographical memoir,The Puzzle People, was named byThe Wall Street Journal as the third best book on doctors' lives[8] and was written in three months.[9]
Recognizing the causative role ofimmunosuppression in the development of post-transplantlymphoproliferative disease and other opportunistic infections and the utility of reversing the immunosuppressed state as the principal treatment;
Thomas E. Starzl Way on the campus of theUniversity of PittsburghEntrance to the Thomas Starzl Biomedical Research Tower at the University of Pittsburgh.
Starzl was named one of the most important people of the Millennium, ranking No. 213, according to the authors of "1,000 Years, 1,000 People: Ranking the Men and Women Who Shaped the Millennium " (Kodansha America, 332 pp.)[1]
Starzl has also receivedhonorary degrees from 26 universities in the United States and abroad, which include 12 in Science, 11 in Medicine, 2 in Humane Letters, and 1 in Law.[27]
In 2006, at a celebration for his 80th birthday, theUniversity of Pittsburgh renamed one of its newest medical research buildings the Thomas E. Starzl Biomedical Science Tower in recognition of his achievements and contributions to the field.[28] On October 15, 2007, the Western Pennsylvania American Liver Foundation and the City of Pittsburgh honored Starzl by dedicating Lothrop Street, near his office and the biomedical research tower bearing his name, as "Thomas E. Starzl Way".[29]
A statue honoring Starzl was unveiled on June 24, 2018 on the University of Pittsburgh campus near the school'sCathedral of Learning.[30]
Having retired from clinical and surgical service since 1991, Starzl devoted his time to research endeavors and remained active as professor of surgery at the University of Pittsburgh School of Medicine and theUniversity of Pittsburgh Medical Center's (UPMC) program named in his honor: the Thomas E. Starzl Transplantation Institute. Since his "retirement," he earned the additional distinctions of being one of the most prolific scientists in the world as well as the most cited scientist in the field of clinical medicine.[32]
^Starzl, Thomas E. (2003).The puzzle people : memoirs of a transplant surgeon. Pittsburgh: University of Pittsburgh Press. p. 40.ISBN0-8229-5836-8.OCLC54022664.
^Verghese, Abraham (July 10, 2010)."Five Best".The Wall Street Journal. RetrievedJuly 31, 2010.
^Werth, Barry (2014).The billion-dollar molecule : the quest for the perfect drug. New York: Simon & Schuster.ISBN978-1-4391-2681-3.OCLC892937368.
Grand-Cross of theMilitary Order of Saint James of the Sword,Portugal (13 November 1995)[31]
