| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Qualification |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | New York Cosmos(F) | 22 | 14 | 5 | 3 | 44 | 21 | +23 | 47 | Playoffs |
| 2 | Indy Eleven | 22 | 11 | 4 | 7 | 36 | 25 | +11 | 37 | |
| 3 | FC Edmonton | 22 | 10 | 6 | 6 | 16 | 14 | +2 | 36 | |
| 4 | Rayo OKC | 22 | 9 | 8 | 5 | 28 | 21 | +7 | 35 | |
| 5 | Miami FC | 22 | 9 | 6 | 7 | 31 | 27 | +4 | 33 | |
| 6 | Fort Lauderdale Strikers | 22 | 7 | 5 | 10 | 19 | 28 | −9 | 26 | |
| 7 | Carolina RailHawks | 22 | 7 | 5 | 10 | 25 | 35 | −10 | 26 | |
| 8 | Minnesota United | 22 | 6 | 7 | 9 | 25 | 25 | 0 | 25 | |
| 9 | Puerto Rico | 22 | 5 | 9 | 8 | 19 | 31 | −12 | 24 | |
| 10 | Tampa Bay Rowdies | 22 | 5 | 8 | 9 | 29 | 32 | −3 | 23 | |
| 11 | Jacksonville Armada | 22 | 5 | 8 | 9 | 25 | 35 | −10 | 23 | |
| 12 | Ottawa Fury | 22 | 5 | 7 | 10 | 23 | 26 | −3 | 22 |