| Combination of | |
|---|---|
| Telmisartan | Angiotensin II receptor antagonist |
| Hydrochlorothiazide | Thiazidediuretic |
| Clinical data | |
| Trade names | Micardis Plus, Micardis HCT, others |
| AHFS/Drugs.com | Professional Drug Facts |
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| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
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| Identifiers | |
| CAS Number | |
| PubChemCID | |
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| CompTox Dashboard(EPA) | |
| Chemical and physical data | |
| Formula | C40H38ClN7O6S2 |
| Molar mass | 812.36 g·mol−1 |
| 3D model (JSmol) | |
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| (verify) | |
Telmisartan/hydrochlorothiazide, sold under the brand nameMicardis HCT among others, is afixed-dose combination medication used to treathigh blood pressure.[3] It is a combination oftelmisartan anangiotensin II receptor antagonist withhydrochlorothiazide adiuretic.[3] It may be used if telmisartan by itself is not sufficient.[6] It is takenby mouth.[6]
Common side effects include dizziness, upper respiratory tract infections, nausea, diarrhea, and tiredness.[3] Severe side effects may includekidney problems,electrolyte problems, andallergic reactions.[3] Use duringpregnancy may harm the baby.[3] Telmisartan works by blocking the effects ofangiotensin II while hydrochlorothiazide works by decreasing thekidneys' ability to retain water.[3]
The combination was approved for medical use in the United States in November 2000,[7][8] and in the European Union in April 2002.[4][5] The combination is on theWorld Health Organization's List of Essential Medicines.[9] It is available as ageneric medication.[6]
