Talk:Pellagra
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Could someone please change the sentence "Pellagra is an endemic disease located in ..." to "Pellagra is an endemic disease in"? When you say "endemic" you already imply the term located and it would be redundant to repeat it. Thanks.85.178.31.153 ([[User talk:85.178.31.153|talk]])10:04, 4 March 2008 (UTC)[reply]
Oops, sorry, just realized the article isn't locked after all. Will change it myself.85.178.31.153 (talk)10:05, 4 March 2008 (UTC)[reply]
Niacin deficiency can occur when both niacin andtryptophan intakes are low (tryptophan can be converted to niacin in the human body). Lysine, AFAIK, has nothing to do with all that. Theniacin page doesn't even mention it, either.Aragorn217:12, 15 May 2005 (UTC)[reply]
Is this problem resolved? The article says a lack of niacin and tryptophan causes pellagra, but then says a lack of available lysine in untreated corn is the problem. The link between those two statements is unclear.Lobosolo02:29, 4 November 2005 (UTC)[reply]
Also, the Joseph Goldberger link redirects to here. Shouldn't there be a separate Goldberger entry, even if it's brief?Lobosolo02:29, 4 November 2005 (UTC)[reply]
Seehexachlorobenzene:"American Pellagra was a disease affecting 250,000 people between 1900-1950 caused by hexochlorobenzene residue from new bleaching and degermination procedures for corn and wheat. Hexachlorobenzene was banned from use in the United States in 1966." --Espoo09:07, 4 May 2006 (UTC)[reply]
It tells symptoms and what is going on superfically but it never mentions whats causing these symptoms and what Pellagra actually is doing to the body. Would someone please add, or explain why it shouldn't.—Precedingunsigned comment added by72.177.232.2 (talk •contribs) 02:39, 14 February 2007
The link to Rankin goes to a disambiguation page. I can't tell which Rankin it refers to.Ben (talk)21:26, 22 March 2008 (UTC)[reply]
needs microanatomy/ histology images with explanation of microscopic findings of the dermatitisTkjazzer (talk)20:46, 25 March 2008 (UTC)[reply]
according to the site which i listed inlist of eponymous medical signs under casal's collar, the disease was first described by françois thiery in 1755, by casal in 1762.—Precedingunsigned comment added byToyokuni3 (talk •contribs)05:02, 11 May 2008 (UTC)[reply]
Some clarification is necessary in the last three sentences in the Epidemiology section, which state"The amino acid deficiency must be balanced by consumption of other sources of protein. It was common amongst prisoners of Soviet labor camps, the infamous Gulag. It can be found in cases of chronic alcoholism." It's not clear whether the "it" in the last two sentences refers to "the amino acid deficiency" that's mentioned in the first of these three sentences or to Pellagra itself. --noosphere01:36, 10 July 2008 (UTC)[reply]
I've removed death and converted the 4 D's to the more realistic and commonly used 3 D's. Death should not be part of the mnemonic or memory aid, since failure of any vitamin, by its very nature, will cause death. Adding death to the list is redundant and frankly fairly stupid. Why would it be that if someone dies you then have to begin considering pellagra? I immplore educators to change, like almost all new textbooks, to the 3 D's; indeed the referenced source uses 3 D's itself. Cheers.--Cpt ricard (talk) 07:12, 9 February 2010 (UTC)"It reminds medical students that it is important to keep pellagra in the differential.99.48.75.121 (talk)17:14, 2 February 2011 (UTC)[reply]
Mexicans created thenixtamalization process, which avoids pellagra. In fact, the lack of pellagra in Mexico and other Latin American countries lead scientists to find out that nixtamalization was a required grain treatment for corn intended for human consumption. Pallagra may be common anywhere else, maybe even the U. S., but not in Mexico.24.44.93.16 (talk) 15:05, 9 April 2010 (UTC)--24.44.93.16 (talk)15:05, 9 April 2010 (UTC)[reply]
Why does this article begin with the (admittedly common] misconception thatniacin can be known as Vitamin B3, a point which some dietary experts would dispute today?ACEOREVIVED (talk)23:34, 28 June 2010 (UTC)[reply]
"Pellagra can be common in people who obtain most of their food energy from maize (often called "corn"), notably rural South America where maize is a staple food. If maize is not nixtamalized, it is a poor source of tryptophan as well as niacin."
This statement is wrong. Nixtamalization will do nothing to increase corn low tryptophan levels since corn is simply deficient in tryptophan in this essential amino acid. I'll correct if nobody else has any objection.81.60.184.222 (talk)19:32, 28 April 2011 (UTC)[reply]
The Prognosis section needs work. It does not cover the case when treatment is given, only when treatment is not given. Are the symptoms and long-term harm reversed upon treatment or are they permanent?CountMacula (talk)20:25, 25 August 2012 (UTC)[reply]
Wild deer in much of North America take corn as a large part of their diets. Are they affected by pellagra? If not, why not?
What about people eating corn on the cob?
Does it matter whether the grain is mature?CountMacula (talk)05:15, 27 October 2012 (UTC)[reply]
"Despite all his efforts few physicians took up his ideas due to necessity of social reform, especially in the land system of that time, which led to many avoidable deaths and stereotypes."
There's no explanation or elaboration on this sentence.— Precedingunsigned comment added by50.0.107.211 (talk)02:11, 8 June 2013 (UTC)[reply]
Also in developed countries mild forms of Pellagra are much common. I know this because I suffered more than 10 years from it. It took me those 10 years how to become healthy again, to find out that I need niacin! For treatment I take 2 doses with 1,5g niacin everyday, and my chronique fatigue and also my skin problems just went away. So flushing is joyful, it's like an immun reaction and makes you healthy. I would appreciate if other people who experienced mild forms of Pellagra would help to improve this article.178.197.225.71 (talk)11:47, 21 August 2013 (UTC)[reply]
Pellagra#United_States currently argues for the theory that corn contains niacin in the form of a hemicellulose-bound "niacytin" that can be liberated bynixtamalization. However, one secondary~tertiary source cited by the nixtamalization article, specifically FAO 1992, seems to quite clearly refute this mechanism of action for nixtamal using multiple sources. It's much more likely that the anti-pellagra action is due to a difference in the digestibility of tryptophan-containing proteins.[1]
There is, however, insufficient information on the effect of germ removal from FAO 1992. The section on Arepas seems suggest that germ removal is associated with a reduction of protein quality (and with "Chavez (1972b)", specifically a loss of tryptophan), but I doubt we can use it to say much about the Beall degerminator.
Artoria2e5🌉05:30, 17 April 2024 (UTC)[reply]
