 | |
| Clinical data | |
|---|---|
| Other names | 5-(1-methylpropyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| |
| CAS Number |
|
| PubChemCID | |
| DrugBank |
|
| ChemSpider |
|
| UNII | |
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.003.719 |
| Chemical and physical data | |
| Formula | C11H16N2O3 |
| Molar mass | 224.260 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
 N Y (what is this?) (verify) | |
Talbutal (Lotusate) is abarbiturate with a short to intermediate duration of action. It is astructural isomer ofbutalbital. Talbutal is a schedule III drug in the U.S.
Talbutal is a short to intermediate-acting barbiturate. Barbiturates act as nonselective depressants of thecentral nervous system (CNS), capable of producing all levels of CNS mood alteration from excitation to mild sedation, hypnosis, and deep coma. In sufficiently high therapeutic doses, barbiturates induceanesthesia.[1]
Talbutal binds at a distinct binding site associated with a Cl− ionophore at theGABAA receptor, increasing the duration of time for which the Cl− ionophore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
Symptoms of acute barbiturate poisoning include drowsiness, confusion, coma, respiratory depression,hypotension,[1] and shock.
 | This articleneeds additional citations forverification. Please helpimprove this article byadding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "Talbutal" – news ·newspapers ·books ·scholar ·JSTOR(December 2009) (Learn how and when to remove this message) |
