TRPM4-IN-5

Identifiers
IUPAC name 4-chloro-2-{[2-(2-chlorophenoxy)acetyl]amino}benzoic acid
CAS Number	351424-20-9
PubChemCID	2264067
ChemSpider	1692848
Chemical and physical data
Formula	C15H11Cl2NO4
Molar mass	340.16 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC=C(C(=C1)OCC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O)Cl
InChI InChI=1S/C15H11Cl2NO4/c16-9-5-6-10(15(20)21)12(7-9)18-14(19)8-22-13-4-2-1-3-11(13)17/h1-7H,8H2,(H,18,19)(H,20,21) Key:CVQCJPCMPGKEDH-UHFFFAOYSA-N

TRPM4-IN-5 is a drug which acts as a moderately potent but highly selective blocker of theTRPM4ion channel, with an IC₅₀ of 1.5 μM.^[1] It is protective against glutamate mediated neuronal excitotoxicity.^[2]

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