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TOE1

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
TOE1
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

2FC6

Identifiers
AliasesTOE1, hCaf1z, target of EGR1, member 1 (nuclear), PCH7, target of EGR1, exonuclease, TOE-1
External IDsOMIM:613931;MGI:1915526;HomoloGene:11823;GeneCards:TOE1;OMA:TOE1 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for TOE1
Genomic location for TOE1
Band1p34.1Start45,340,052bp[1]
End45,343,973bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for TOE1
Genomic location for TOE1
Band4|4 D1Start116,651,507bp[2]
End116,664,837bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • olfactory bulb

  • gonad

  • parotid gland

  • mucosa of transverse colon

  • right lobe of thyroid gland

  • left testis

  • granulocyte

  • right testis

  • smooth muscle tissue

  • rectum
Top expressed in
  • primitive streak

  • renal corpuscle

  • morula

  • blastocyst

  • spermatocyte

  • epiblast

  • superior cervical ganglion

  • medullary collecting duct

  • seminal vesicula

  • ureter
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

114034

68276

Ensembl

ENSG00000132773

ENSMUSG00000028688

UniProt

Q96GM8

Q9D2E2

RefSeq (mRNA)

NM_025077

NM_026654

RefSeq (protein)

NP_079353

NP_080930

Location (UCSC)Chr 1: 45.34 – 45.34 MbChr 4: 116.65 – 116.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Target of EGR1 protein 1 is aprotein that in humans is encoded by theTOE1gene.[5][6]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000132773 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000028688 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^De Belle I, Wu JX, Sperandio S, Mercola D, Adamson ED (Apr 2003)."In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1".J Biol Chem.278 (16):14306–12.doi:10.1074/jbc.M210502200.PMID 12562764.
  6. ^"Entrez Gene: TOE1 target of EGR1, member 1 (nuclear)".

Further reading

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