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THCP-O-acetate

From Wikipedia, the free encyclopedia
Chemical compound

Pharmaceutical compound
THCP-O-acetate
Identifiers
  • (6aR,10aR)-3-heptyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-yl acetate
CAS Number
ChemSpider
Chemical and physical data
FormulaC25H36O3
Molar mass384.560 g·mol−1
3D model (JSmol)
  • CC(=O)Oc1cc(CCCCCCC)cc2OC(C)(C)[C@@H]3CCC(C)=C[C@H]3c21
  • InChI=1S/C25H36O3/c1-6-7-8-9-10-11-19-15-22(27-18(3)26)24-20-14-17(2)12-13-21(20)25(4,5)28-23(24)16-19/h14-16,20-21H,6-13H2,1-5H3/t20-,21-/m1/s1
  • Key:OXMUZNKOOOITQD-NHCUHLMSSA-N

THCP-O-acetate (THCP-O) is a semi-synthetic derivative oftetrahydrocannabiphorol (THCP) derived byacetylation of the OH group. It has been found as a component of grey-market cannabis products such as e-cigarette liquids and edible gummy lollies, and is allegedly a potent and long-lasting psychoactive cannabinoid.[1]

Toxicity

[edit]

In 2022, researchers at Portland State University who screened for the presence of reacted ketene as N-benzylacetamide reported thatVitamin E acetate,CBD-acetate,CBN-acetate and THC-O-acetate may break down to releaseketene gas when heated at 340 °C (644 °F).[2][3]

Legality

[edit]

Japan banned THCP-O-Acetate along withHHCP on December 26, 2023.[4]

See also

[edit]

References

[edit]
  1. ^Erickson BE (2023)."Waiting for CBD regulations in the US".Chemical & Engineering News.101 (28):17–19.doi:10.1021/cen-10128-feature1.S2CID 261318144.
  2. ^Munger KR, Jensen RP, Strongin RM (July 2022). "Vaping Cannabinoid Acetates Leads to Ketene Formation".Chemical Research in Toxicology.35 (7):1202–1205.doi:10.1021/acs.chemrestox.2c00170.PMID 35801872.
  3. ^Sagen J, Paikoff S, Ford J, Newman D, Jyot J (2022)."Proceedings of the 2022 Cannabis Clinical Outcomes Research Conference (CCORC) Orlando, FL, USA, May 19-20, 2022".Medical Cannabis and Cannabinoids.5 (1):142–158.doi:10.1159/000527081.PMC 9729860.
  4. ^"Japan bans sale of 38 goods with synthetic cannabis compounds".The Japan Times. 22 December 2023.
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