 | |
| Names | |
|---|---|
| Preferred IUPAC name N,N-Diethyl-N-methyl-3-[(methylcarbamoyl)oxy]anilinium iodide | |
| Other names AR-16, TL-1217 | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
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| Properties | |
| C13H21IN2O2 | |
| Molar mass | 364.227 g·mol−1 |
| Related compounds | |
Related compounds | Neostigmine Miotine |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 129 μg/kg (Subcutaneous, mice)[1] 75 μg/kg (Subcutaneous, cats)[1] 75 μg/kg (Subcutaneous, dogs)[1] 150 μg/kg (Subcutaneous, rabbits)[1] 122.5 μg/kg (Intramuscular, rats)[2] |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
T-1123 is acarbamate-basedacetylcholinesterase inhibitor. It was investigated as a chemical warfare agent starting in 1940. It does not go through theblood-brain barrier due to the charge on quaternary nitrogen. The antidote isatropine.[3] T-1123 is a quaternary ammonium ion. Aphenyl carbamate ester is bonded in the meta position to the nitrogen on a diethylmethyl amine. The chloride and methylsulfate salt of T-1123 is TL-1299 and TL-1317, respectively.
T-1123 can be produced fromm-diethylaminophenol,methyl isocyanate andmethyl iodide. First, m-diethylaminophenol is reacted with methyl isocyanate to produce a methylcarbamate. The resulting methylcarbamate is then reacted with methyl iodide to produce T-1123.[1]
