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Sulfathiourea

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Chemical compound

Pharmaceutical compound

Sulfathiourea
Clinical data

Other names	(4-aminophenyl)sulfonylthiourea
ATC code	J01EB08 (WHO)
Identifiers
IUPAC name 4-amino-N-(aminocarbonothioyl)benzenesulfonamide
CAS Number	515-49-1
PubChemCID	3000579
ChemSpider	2272143^Y
UNII	MXF9G4I1V5
KEGG	D07239^Y
ChEBI	CHEBI:131723
CompTox Dashboard(EPA)	DTXSID4046868
ECHA InfoCard	100.007.457
Chemical and physical data
Formula	C₇H₉N₃O₂S₂
Molar mass	231.29 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c1ccc(N)cc1)NC(=S)N
InChI InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)^Y Key:UEMLYRZWLVXWRU-UHFFFAOYSA-N^Y
(verify)

Sulfathiourea is asulfonamide antibacterial.^[1]

^Schoog M (November 1953). "[Sulfathiourea, chemistry, pharmacology and clinical aspects]".Zeitschrift für Haut- und Geschlechtskrankheiten (in German).15 (10):315–8.PMID 13137202.

Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)

Short-acting	Sulfaisodimidine Sulfamethizole Sulfadimidine (Sulfamethazine,Sulfadimerazine,Sulfadimezine) Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole,Succinylsulfathiazole) Sulfathiourea
Intermediate-acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole
Long-acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Mafenide Sulfacetamide Sulfaclozine Sulfadicramide Sulfaguanidine Sulfametrole Sulfanitran

Combinations

Other DHPS inhibitors

Quinolones
(inhibit bacterial
topoisomerase
and/orDNA gyrase,
thereby inhibiting
DNA replication)

2nd generation	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡/Levonadifloxacin/Alalevonadifloxacin Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡
3rd generation	Levofloxacin^# Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡
4th generation	Besifloxacin Delafloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin^# Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡
Veterinary	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin^‡