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Serostatus

From Wikipedia, the free encyclopedia
(Redirected fromSeropositive)
Presence of a marker in blood

Serostatus refers to the presence or absence of aserological marker in the blood. The presence of detectable levels of a specific marker within theserum is consideredseropositivity, while the absence of such levels is consideredseronegativity.

HIV/AIDS

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The term serostatus is commonly used in HIV/AIDS prevention efforts. In the late 20th and early 21st centuries, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.[1]

Autoimmune disease

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Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation.[2][3][4] Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.[5][6]

See also

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References

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  1. ^Janssen RS, Holtgrave DR, Valdiserri RO, et al. (July 2001)."The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals".American Journal of Public Health.91 (7). American Public Health Association:1019–1024.doi:10.2105/AJPH.91.7.1019.ISSN 1541-0048.PMC 1446705.PMID 11441723.
  2. ^Jarius S, Ruprecht K, Wildemann B, et al. (January 2012)."Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients".Journal of Neuroinflammation.9 (1). BioMed Central: 14.doi:10.1186/1742-2094-9-14.PMC 3283476.PMID 22260418.
  3. ^Ajeganova S, Huizinga TW (November 2014). "Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?".Nature Reviews Rheumatology.11 (1). Nature Publishing Group:8–9.doi:10.1038/nrrheum.2014.194.ISSN 1759-4804.PMID 25403158.S2CID 1405551.
  4. ^Balasubramanian G, Sugumar A, Smyrk TC, et al. (2012)."Demystifying seronegative autoimmune pancreatitis".Pancreatology.12 (4). Elsevier:289–294.doi:10.1016/j.pan.2012.05.003.PMID 22898628.
  5. ^Somers K, Geusens P, Elewaut D, et al. (February 2011). "Novel autoantibody markers for early and seronegative rheumatoid arthritis".Journal of Autoimmunity.36 (1). Elsevier:33–46.doi:10.1016/j.jaut.2010.10.003.ISSN 0896-8411.PMID 21071175.
  6. ^Pevzner A, Schoser B, Peters K, et al. (August 2011)."Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis"(PDF).Journal of Neurology.259 (3). Springer-Verlag:427–435.doi:10.1007/s00415-011-6194-7.ISSN 1432-1459.PMID 21814823.S2CID 13125248.
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