Grisolía published over 400 scientific papers and was involved with numerous organizations in Spain and other countries.[1] It is impossible to summarize such a large output in a few words, but some references give an indication of his work and publications, many of which were concerned with enzymes. Much of his first work concerned the biochemistry ofcitrulline,[2] and he later worked on phosphoglycerate mutase,[3] carbamoyl-phosphate synthetase[4][5] and other enzymes.He has held various positions, including President of the Scientific Coordination Committee of theHuman Genome Project forUNESCO.
He died in Valencia in 2022 at the age of 99.[1][6]
^Britton, H G; Carreras, J; Grisolia, S (1971). "Mechanism of action of 2,3-diphosphoglycerate-independent phosphoglycerate mutase".Biochemistry.10 (24):4522–4533.doi:10.1021/bi00800a028.PMID5168977.
^Rubio, V; Grisolia, S (1977). "Mechanism of mitochondrial carbamoyl-phosphate synthetase - synthesis and properties of active CO2, precursor of carbamoyl phosphate".Biochemistry.16 (2):321–329.doi:10.1021/bi00621a025.PMID13811.
^Rubio, V; Britton, H G; Grisolia, S; Sproat, B S; Lowe, G (1981). "Mechanism of activation of bicarbonate ion by mitochondrial carbamoyl-phosphate synthetase — formation of enzyme-bound adenosine-diphosphate from the adenosine-triphosphate that yields inorganic-phosphate".Biochemistry.20 (7):1969–1974.doi:10.1021/bi00510a036.PMID6261808.
.jpg)
