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Sanofi–Translate Bio COVID-19 vaccine

From Wikipedia, the free encyclopedia
Vaccine candidate against COVID-19

Pharmaceutical compound
Sanofi–Translate Bio COVID-19 vaccine
Vaccine description
TargetSARS-CoV-2
Vaccine typemRNA
Clinical data
Other namesMRT5500, VAW00001
Routes of
administration
Intramuscular
Legal status
Legal status
Identifiers
CAS Number
Part ofa series on the
COVID-19 pandemic
Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
virus iconCOVID-19 portal

TheSanofi–Translate Bio COVID-19 vaccine, also known asMRT5500 orVAW00001, was aCOVID-19 vaccine candidate developed bySanofi Pasteur andTranslate Bio.[3][4] The development was stopped in September 2021.[5]

History

[edit]

In June 2020, Sanofi, after lagging behind its competitors, "accelerated" the development of the vaccine via the smaller biotech firm Translate Bio, with aUS$425 million partnership.[6]

Development of the vaccine halted in September 2021, with Sanofi citing the difficulty of running placebo-controlled studies with other mRNA vaccines (such asPfizer's andModerna's) already on the market. Despite this, the company reported "promising results" in its initial trials.[5]Sanofi has continued testingits recombinant protein vaccine, developed collaboratively withGlaxoSmithKline, to serve as a booster dose for other COVID-19 vaccines.[5]

References

[edit]
  1. ^Abboud L (28 September 2021)."Sanofi stops development of Covid vaccine based on mRNA technology". Financial Times.
  2. ^"Patent Landscape Report COVID-19-related vaccines and therapeutics"(PDF).
  3. ^"Sanofi and Translate Bio initiate Phase 1/2 clinical trial of mRNA COVID-19 vaccine candidate". Sanofi. 12 March 2021. Archived fromthe original on 9 October 2021. Retrieved20 March 2021.
  4. ^"Study of mRNA Vaccine Formulation Against COVID-19 in Healthy Adults 18 Years of Age and Older (VAW00001)". United States National Library of Medicine. Retrieved20 March 2021.
  5. ^abc"Sanofi drops plans for messenger RNA vaccine against virus".Associated Press. 28 September 2021.Archived from the original on 14 October 2021. Retrieved7 October 2021.
  6. ^Branswell H, Feuerstein A (23 June 2020)."Sanofi, a straggler in the Covid-19 vaccine race, accelerates its plans".STAT.Archived from the original on 20 October 2021. Retrieved7 August 2020.

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