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Salicylanilide

From Wikipedia, the free encyclopedia
Salicylanilide[1]
Names
Preferred IUPAC name
2-Hydroxy-N-phenylbenzamide
Other names
2-Hydroxybenzanilide
Identifiers
3D model (JSmol)
1108135
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard100.001.571Edit this at Wikidata
EC Number
  • 201-727-8
KEGG
UNII
  • InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) ☒N
    Key: WKEDVNSFRWHDNR-UHFFFAOYSA-N ☒N
  • InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16)
    Key: WKEDVNSFRWHDNR-UHFFFAOYAI
  • C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
Properties
C13H11NO2
Molar mass213.236 g·mol−1
AppearanceWhite to off-white crystalline solid
Melting point136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
GHS labelling:[2]
GHS07: Exclamation markGHS09: Environmental hazard
Warning
H315,H319,H335,H400
P261,P264,P271,P273,P280,P302+P352,P304+P340,P305+P351+P338,P312,P321,P332+P313,P337+P313,P362,P391,P403+P233,P405,P501
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

Salicylanilide is a chemical compound which is theamide ofsalicylic acid andaniline. It is classified as both asalicylamide and ananilide.[3]

Derivatives of salicylanilide have a variety of pharmacological uses.Chlorinated derivatives includingniclosamide,oxyclozanide, andrafoxanide are used asanthelmintics, especially asflukicides.Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as topicalantibacterials andantifungals.


References

[edit]
  1. ^Salicylanilide at chemicalland21.com
  2. ^"Salicylanilide".pubchem.ncbi.nlm.nih.gov. Retrieved13 December 2021.
  3. ^Salicylanilides at the U.S. National Library of MedicineMedical Subject Headings (MeSH)
Authority control databases: NationalEdit this at Wikidata
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