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| Other names | 5,6,7,8-tetrahydro-3-(5-methoxy-1,3,4-oxadiazol-2-yl)-6-(phenylmethyl)-1,6-naphthyridin-2(1H)-one |
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| Formula | C18H18N4O3 |
| Molar mass | 338.367 g·mol−1 |
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SX-3228 is asedative andhypnotic drug used in scientific research. It has similar effects to sedative-hypnoticbenzodiazepine drugs, but is structurally distinct and so is classed as anonbenzodiazepine hypnotic.
SX-3228 is a subtype-selectiveGABAApositive allosteric modulator acting primarily at the α1 subtype. It thus has similar effects to other α1-selective drugs such aszolpidem andzaleplon in animal studies.[1][2] It only partly substitutes for ethanol, and is a strong sedative-hypnotic with only limitedanxiolytic effects which appear only at doses that also produce significant sedation.[3][4]