Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

Solute carrier organic anion transporter family member 1A2

From Wikipedia, the free encyclopedia
(Redirected fromSLCO1A2)
SLCO1A2
Identifiers
AliasesSLCO1A2, OATP, OATP-A, OATP1A2, SLC21A3, solute carrier organic anion transporter family member 1A2
External IDsOMIM:602883;MGI:1351865;HomoloGene:56603;GeneCards:SLCO1A2;OMA:SLCO1A2 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for SLCO1A2
Genomic location for SLCO1A2
Band12p12.1Start21,264,600bp[1]
End21,419,594bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for SLCO1A2
Genomic location for SLCO1A2
Band6|6 G2Start142,179,953bp[2]
End142,268,707bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • C1 segment

  • corpus callosum

  • amygdala

  • optic nerve

  • putamen

  • substantia nigra

  • hypothalamus

  • caudate nucleus

  • hippocampus proper

  • Brodmann area 9
Top expressed in
  • seminal vesicula

  • vestibular membrane of cochlear duct

  • stria vascularis

  • vestibular sensory epithelium

  • salivary gland

  • choroid plexus

  • Epithelium of choroid plexus

  • olfactory epithelium

  • submandibular gland

  • lacrimal gland
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

6579

108096

Ensembl

ENSG00000084453

ENSMUSG00000063975

UniProt

P46721

Q91YY5

RefSeq (mRNA)

NM_005075
NM_021094
NM_134431

NM_001267707
NM_130861

RefSeq (protein)

NP_066580
NP_602307

NP_001254636
NP_570931

Location (UCSC)Chr 12: 21.26 – 21.42 MbChr 6: 142.18 – 142.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier organic anion transporter family member 1A2 is aprotein that in humans is encoded by theSLCO1A2gene.[5][6]

This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.[6]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000084453 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000063975 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Kullak-Ublick GA, Beuers U, Meier PJ, Domdey H, Paumgartner G (Apr 1997). "Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization".J Hepatol.25 (6):985–7.doi:10.1016/S0168-8278(96)80307-2.PMID 9007731.
  6. ^ab"Entrez Gene: SLCO1A2 solute carrier organic anion transporter family, member 1A2".

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
SLC41–48
(41):
(42):
(43):
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)
Stub icon

Thismembrane protein–related article is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Solute_carrier_organic_anion_transporter_family_member_1A2&oldid=1300577047"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp