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Sodium/hydrogen exchanger 5

From Wikipedia, the free encyclopedia
(Redirected fromSLC9A5)
Protein-coding gene in the species Homo sapiens
SLC9A5
Identifiers
AliasesSLC9A5, NHE5, solute carrier family 9 member A5
External IDsOMIM:600477;MGI:2685542;HomoloGene:31247;GeneCards:SLC9A5;OMA:SLC9A5 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for SLC9A5
Genomic location for SLC9A5
Band16q22.1Start67,237,683bp[1]
End67,272,191bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for SLC9A5
Genomic location for SLC9A5
Band8|8 D3Start105,348,843bp[2]
End105,369,881bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right hemisphere of cerebellum

  • spleen

  • stromal cell of endometrium

  • nucleus accumbens

  • putamen

  • caudate nucleus

  • cerebellar vermis

  • testicle

  • right frontal lobe

  • dorsal motor nucleus of vagus nerve
Top expressed in
  • spermatocyte

  • superior frontal gyrus

  • cerebellar cortex

  • neural layer of retina

  • primary visual cortex

  • lumbar subsegment of spinal cord

  • seminiferous tubule

  • tail of embryo

  • ventricular zone

  • cerebellar vermis
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

6553

277973

Ensembl

ENSG00000135740

ENSMUSG00000014786

UniProt

Q14940

B2RXE2

RefSeq (mRNA)
NM_004594
NM_001323971
NM_001323972
NM_001323973
NM_001323974

NM_001323975

NM_001081332

RefSeq (protein)
NP_001310900
NP_001310901
NP_001310902
NP_001310903
NP_001310904

NP_004585

NP_001074801

Location (UCSC)Chr 16: 67.24 – 67.27 MbChr 8: 105.35 – 105.37 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sodium/hydrogen exchanger 5 is aprotein that in humans is encoded by theSLC9A5gene.[5][6][7]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000135740 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000014786 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Klanke CA, Su YR, Callen DF, Wang Z, Meneton P, Baird N, Kandasamy RA, Orlowski J, Otterud BE, Leppert M, et al. (Jun 1995). "Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1".Genomics.25 (3):615–22.doi:10.1016/0888-7543(95)80002-4.PMID 7759094.
  6. ^Attaphitaya S, Park K, Melvin JE (Mar 1999)."Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain".J Biol Chem.274 (7):4383–8.doi:10.1074/jbc.274.7.4383.PMID 9933642.
  7. ^"Entrez Gene: SLC9A5 solute carrier family 9 (sodium/hydrogen exchanger), member 5".

Further reading

[edit]
By group
SLC1–10
(1):
(2):
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(5):
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SLC11–20
(11):
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SLC21–30
(21):
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SLC31–40
(31):
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SLC41–48
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SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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