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Y+L amino acid transporter 2

From Wikipedia, the free encyclopedia
(Redirected fromSLC7A6)
Protein-coding gene in the species Homo sapiens

SLC7A6
Identifiers
AliasesSLC7A6, LAT-2, LAT3, y+LAT-2, solute carrier family 7 member 6
External IDsOMIM:605641;MGI:2142598;HomoloGene:62496;GeneCards:SLC7A6;OMA:SLC7A6 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for SLC7A6
Genomic location for SLC7A6
Band16q22.1Start68,264,516bp[1]
End68,301,823bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for SLC7A6
Genomic location for SLC7A6
Band8|8 D3Start106,895,489bp[2]
End106,925,338bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • apex of heart

  • gastrocnemius muscle

  • gastric mucosa

  • subcutaneous adipose tissue

  • tibialis anterior muscle

  • left ventricle

  • tibial nerve

  • abdominal fat

  • left lobe of thyroid gland

  • right auricle
Top expressed in
  • spermatocyte

  • primitive streak

  • embryo

  • neural tube

  • external carotid artery

  • abdominal wall

  • epiblast

  • ventricular zone

  • internal carotid artery

  • otic vesicle
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9057

330836

Ensembl

ENSG00000103064

ENSMUSG00000031904

UniProt

Q92536

Q8BGK6

RefSeq (mRNA)

NM_001076785
NM_003983

NM_178798
NM_001357381
NM_001357382

RefSeq (protein)

NP_001070253
NP_003974
NP_001070253.1
NP_003974.3

NP_848913
NP_001344310
NP_001344311

Location (UCSC)Chr 16: 68.26 – 68.3 MbChr 8: 106.9 – 106.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Y+L amino acid transporter 2, also known ascationic amino acid transporter, y+ system, is aprotein that in humans is encoded by theSLC7A6gene.[5][6]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000103064 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000031904 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: solute carrier family 7 (cationic amino acid transporter".
  6. ^Pfeiffer R, Rossier G, Spindler B, Meier C, Kühn L, Verrey F (January 1999)."Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family".The EMBO Journal.18 (1):49–57.doi:10.1093/emboj/18.1.49.PMC 1171101.PMID 9878049.

Further reading

[edit]
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
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SLC11–20
(11):
(12):
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(14):
(15):
(16):
(17):
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(19):
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SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
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SLC31–40
(31):
(32):
(33):
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SLC41–48
(41):
(42):
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(45):
(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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