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Cationic amino acid transporter 4

From Wikipedia, the free encyclopedia
(Redirected fromSLC7A4)
Protein found in humans
SLC7A4
Identifiers
AliasesSLC7A4, CAT-4, CAT4, HCAT3, VH, solute carrier family 7 member 4
External IDsOMIM:603752;MGI:2146512;HomoloGene:20883;GeneCards:SLC7A4;OMA:SLC7A4 - orthologs
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for SLC7A4
Genomic location for SLC7A4
Band22q11.21Start21,028,718bp[1]
End21,032,840bp[1]
Gene location (Mouse)
Chromosome 16 (mouse)
Chr.Chromosome 16 (mouse)[2]
Chromosome 16 (mouse)
Genomic location for SLC7A4
Genomic location for SLC7A4
Band16|16 A3Start17,389,882bp[2]
End17,401,078bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right testis

  • left testis

  • prefrontal cortex

  • right hemisphere of cerebellum

  • right adrenal gland

  • right adrenal cortex

  • gonad

  • right frontal lobe

  • left adrenal cortex

  • hypothalamus
Top expressed in
  • dentate gyrus of hippocampal formation granule cell

  • seminal vesicula

  • superior frontal gyrus

  • primary visual cortex

  • parotid gland

  • right ventricle

  • hippocampus proper

  • lacrimal gland

  • Region I of hippocampus proper

  • prefrontal cortex
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

6545

224022

Ensembl

ENSG00000099960

ENSMUSG00000022756

UniProt

O43246

Q8BLQ7

RefSeq (mRNA)

NM_004173

NM_144852
NM_001359891
NM_001359892
NM_001359893

RefSeq (protein)

NP_004164

NP_659101
NP_001346820
NP_001346821
NP_001346822

Location (UCSC)Chr 22: 21.03 – 21.03 MbChr 16: 17.39 – 17.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cationic amino acid transporter 4 is aprotein that in humans is encoded by theSLC7A4gene.[5][6][7]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000099960 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000022756 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Sperandeo MP, Borsani G, Incerti B, Zollo M, Rossi E, Zuffardi O, Castaldo P, Taglialatela M, Andria G, Sebastio G (Aug 1998). "The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome".Genomics.49 (2):230–6.doi:10.1006/geno.1998.5252.hdl:11566/82078.PMID 9598310.
  6. ^Hammermann R, Brunn G, Racke K (Oct 2001). "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4".Amino Acids.21 (2):211–9.doi:10.1007/s007260170029.PMID 11665818.S2CID 30892800.
  7. ^"Entrez Gene: SLC7A4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4".

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

By group
SLC1–10
(1):
(2):
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SLC11–20
(11):
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SLC21–30
(21):
(22):
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SLC31–40
(31):
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SLC41–48
(41):
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(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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