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Zinc transporter ZIP10

From Wikipedia, the free encyclopedia
(Redirected fromSLC39A10)
Protein found in humans
SLC39A10
Identifiers
AliasesSLC39A10, LZT-Hs2, solute carrier family 39 member 10
External IDsOMIM:608733;MGI:1914515;HomoloGene:34076;GeneCards:SLC39A10;OMA:SLC39A10 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for SLC39A10
Genomic location for SLC39A10
Band2q32.3Start195,575,977bp[1]
End195,737,702bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for SLC39A10
Genomic location for SLC39A10
Band1|1 C1.1Start46,846,704bp[2]
End46,932,012bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • middle temporal gyrus

  • secondary oocyte

  • Brodmann area 46

  • superior frontal gyrus

  • Brodmann area 23

  • germinal epithelium

  • postcentral gyrus

  • right lobe of thyroid gland

  • dorsolateral prefrontal cortex

  • Brodmann area 9
Top expressed in
  • hand

  • hair follicle

  • otolith organ

  • utricle

  • secondary oocyte

  • primitive streak

  • primary motor cortex

  • cingulate gyrus

  • piriform cortex

  • primary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

57181

227059

Ensembl

ENSG00000196950

ENSMUSG00000025986

UniProt

Q9ULF5

Q6P5F6

RefSeq (mRNA)

NM_001127257
NM_020342

NM_172653
NM_001356416
NM_001356417

RefSeq (protein)

NP_001120729
NP_065075

NP_766241
NP_001343345
NP_001343346

Location (UCSC)Chr 2: 195.58 – 195.74 MbChr 1: 46.85 – 46.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc transporter ZIP10, also known assolute carrier family 39 member 10, is aprotein that in humans is encoded by theSLC39A10gene.[5] ZIP10 belongs to a subfamily of proteins that show structural characteristics ofzinc transporters, and have 14 members in the human genome:ZIP1, ZIP2, ZIP3, ZIP4, ZIP5, ZIP6,ZIP7, ZIP8,ZIP9,ZIP10, ZIP11, ZIP12, ZIP13 and ZIP14.[5][6]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000196950 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000025986 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^abTaylor KM, Morgan HE, Smart K, Zahari NM, Pumford S, Ellis IO, Robertson JF, Nicholson RI (Jul–Aug 2007)."The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer".Mol Med.13 (7–8):396–406.doi:10.2119/2007-00040.Taylor.PMC 1936980.PMID 17673939.
  6. ^Eide DJ (February 2004). "The SLC39 family of metal ion transporters".Pflügers Arch.447 (5):796–800.doi:10.1007/s00424-003-1074-3.PMID 12748861.S2CID 11765308.

Further reading

[edit]
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
SLC41–48
(41):
(42):
(43):
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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