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SLC38A5

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
SLC38A5
Identifiers
AliasesSLC38A5, JM24, SN2, SNAT5, pp7194, solute carrier family 38 member 5
External IDsOMIM:300649;MGI:2148066;HomoloGene:24917;GeneCards:SLC38A5;OMA:SLC38A5 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for SLC38A5
Genomic location for SLC38A5
BandXp11.23Start48,458,537bp[1]
End48,470,260bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for SLC38A5
Genomic location for SLC38A5
BandX|X A1.1Start8,137,372bp[2]
End8,146,418bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • bone marrow cells

  • stromal cell of endometrium

  • upper lobe of left lung

  • C1 segment

  • mucosa of transverse colon

  • left lobe of thyroid gland

  • ganglionic eminence

  • right lobe of thyroid gland

  • right frontal lobe
Top expressed in
  • fetal liver hematopoietic progenitor cell

  • cumulus cell

  • tibiofemoral joint

  • lumbar subsegment of spinal cord

  • left lung lobe

  • blood

  • pyloric antrum

  • Ileal epithelium

  • perirhinal cortex

  • medial ganglionic eminence
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

92745

209837

Ensembl

ENSG00000017483

ENSMUSG00000031170

UniProt

Q8WUX1

Q3U1J0

RefSeq (mRNA)

NM_033518

NM_172479

RefSeq (protein)

NP_277053

NP_766067

Location (UCSC)Chr X: 48.46 – 48.47 MbChr X: 8.14 – 8.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 38 member 5 is aprotein that in humans is encoded by the SLC38A5gene.[5]

Function

[edit]

The protein encoded by this gene is a system N sodium-coupledamino acid transporter. The encoded protein transportsglutamine,asparagine,histidine,serine,alanine, andglycine across thecell membrane, but does not transport charged amino acids,imino acids, orN-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined.

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000017483Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000031170Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: Solute carrier family 38 member 5". Retrieved2017-10-07.

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


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