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Vesicular inhibitory amino acid transporter

From Wikipedia, the free encyclopedia
(Redirected fromSLC32A1)
Protein-coding gene in the species Homo sapiens
SLC32A1
Identifiers
AliasesSLC32A1, VGAT, VIAAT, solute carrier family 32 member 1
External IDsOMIM:616440;MGI:1194488;HomoloGene:56451;GeneCards:SLC32A1;OMA:SLC32A1 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for SLC32A1
Genomic location for SLC32A1
Band20q11.23Start38,724,486bp[1]
End38,729,372bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for SLC32A1
Genomic location for SLC32A1
Band2|2 H1Start158,452,687bp[2]
End158,457,668bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • nucleus accumbens

  • putamen

  • prefrontal cortex

  • caudate nucleus

  • endothelial cell

  • external globus pallidus

  • cingulate gyrus

  • anterior cingulate cortex

  • middle temporal gyrus

  • right frontal lobe
Top expressed in
  • dorsal tegmental nucleus

  • nucleus accumbens

  • nucleus of stria terminalis

  • lateral septal nucleus

  • superior colliculus

  • globus pallidus

  • central gray substance of midbrain

  • medulla oblongata

  • Rostral migratory stream

  • olfactory tubercle
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

140679

22348

Ensembl

ENSG00000101438

ENSMUSG00000037771

UniProt

Q9H598

O35633

RefSeq (mRNA)

NM_080552

NM_009508

RefSeq (protein)

NP_542119

NP_033534

Location (UCSC)Chr 20: 38.72 – 38.73 MbChr 2: 158.45 – 158.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Vesicular inhibitory amino acid transporter is aprotein that in humans is encoded by theSLC32A1gene.[5]

The protein encoded by this gene is an integral membrane protein involved ingamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000101438 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000037771 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1".

Further reading

[edit]
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
SLC41–48
(41):
(42):
(43):
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)
GABATooltip γ-Aminobutyric acidmetabolism andtransportmodulators
Transporter
GATTooltip GABA transporter
VIAATTooltip Vesicular inhibitory amino acid transporter
Enzyme
GADTooltip Glutamate decarboxylase
GABA-TTooltip γ-Aminobutyrate aminotransferase
Other
Antivitamin B6


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