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Equilibrative nucleoside transporter 2

From Wikipedia, the free encyclopedia
(Redirected fromSLC29A2)
Protein-coding gene in the species Homo sapiens
SLC29A2
Identifiers
AliasesSLC29A2, DER12, ENT2, HNP36, Equilibrative nucleoside transporter 2, solute carrier family 29 member 2
External IDsOMIM:602110;MGI:1345278;HomoloGene:37493;GeneCards:SLC29A2;OMA:SLC29A2 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for SLC29A2
Genomic location for SLC29A2
Band11q13.2Start66,362,521bp[1]
End66,372,214bp[1]
Gene location (Mouse)
Chromosome 19 (mouse)
Chr.Chromosome 19 (mouse)[2]
Chromosome 19 (mouse)
Genomic location for SLC29A2
Genomic location for SLC29A2
Band19|19 AStart5,023,860bp[2]
End5,031,972bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gastrocnemius muscle

  • muscle of thigh

  • apex of heart

  • mucosa of transverse colon

  • right hemisphere of cerebellum

  • right auricle of heart

  • body of tongue

  • vastus lateralis muscle

  • skeletal muscle tissue

  • Skeletal muscle tissue of rectus abdominis
Top expressed in
  • neural layer of retina

  • yolk sac

  • tail of embryo

  • genital tubercle

  • embryo

  • embryo

  • epiblast

  • superior frontal gyrus

  • muscle of thigh

  • dentate gyrus of hippocampal formation granule cell
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

3177

13340

Ensembl

ENSG00000174669

ENSMUSG00000024891

UniProt

Q14542

Q61672

RefSeq (mRNA)

NM_001300868
NM_001300869
NM_001532

NM_007854

RefSeq (protein)

NP_001287797
NP_001287798
NP_001523

NP_031880

Location (UCSC)Chr 11: 66.36 – 66.37 MbChr 19: 5.02 – 5.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Equilibrative nucleoside transporter 2 (ENT2) is aprotein that in humans is encoded by theSLC29A2gene.[5][6][7]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000174669 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000024891 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Williams JB, Rexer B, Sirripurapu S, John S, Goldstein R, Phillips JA III, Haley LL, Sait SN, Shows TB, Smith CM, Gerhard DS (Sep 1997). "The human HNP36 gene is localized to chromosome 11q13 and produces alternative transcripts that are not mutated in multiple endocrine neoplasia, type 1 (MEN I) syndrome".Genomics.42 (2):325–30.doi:10.1006/geno.1997.4751.PMID 9192854.
  6. ^Crawford CR, Patel DH, Naeve C, Belt JA (Mar 1998)."Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line".J Biol Chem.273 (9):5288–93.doi:10.1074/jbc.273.9.5288.PMID 9478986.
  7. ^"Entrez Gene: SLC29A2 solute carrier family 29 (nucleoside transporters), member 2".

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

Receptor
(ligands)
P0 (adenine)
P1
(adenosine)
P2
(nucleotide)
P2X
(ATPTooltip Adenosine triphosphate)
P2Y
Transporter
(blockers)
CNTsTooltip Concentrative nucleoside transporters
ENTsTooltip Equilibrative nucleoside transporters
PMATTooltip Plasma membrane monoamine transporter
Enzyme
(inhibitors)
XOTooltip Xanthine oxidase
Others
Others
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
SLC41–48
(41):
(42):
(43):
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter,Cotransporter
Antiporter (exchanger)


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