Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

SIGLEC7

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
SIGLEC7
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

1NKO,1O7S,1O7V,2DF3,2G5R,2HRL

Identifiers
AliasesSIGLEC7, AIRM1, CD328, CDw328, D-siglec, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2, p75, p75/AIRM1, sialic acid binding Ig like lectin 7, AIRM-1
External IDsOMIM:604410;MGI:1932475;HomoloGene:130668;GeneCards:SIGLEC7;OMA:SIGLEC7 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for SIGLEC7
Genomic location for SIGLEC7
Band19q13.41Start51,142,299bp[1]
End51,153,526bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for SIGLEC7
Genomic location for SIGLEC7
Band7 B3|7Start43,300,494bp[2]
End43,309,585bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • monocyte

  • blood

  • spleen

  • gonad

  • testicle

  • appendix

  • amniotic fluid

  • lymph node

  • right adrenal cortex
Top expressed in
  • granulocyte

  • zygote

  • secondary oocyte

  • spleen

  • blood

  • embryo

  • embryo

  • right kidney

  • bone marrow

  • primary oocyte
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

27036

83382

Ensembl

ENSG00000168995

ENSMUSG00000030474

UniProt

Q9Y286

Q91Y57

RefSeq (mRNA)

NM_001277201
NM_014385
NM_016543

NM_031181

RefSeq (protein)

NP_001264130
NP_055200
NP_057627

NP_112458

Location (UCSC)Chr 19: 51.14 – 51.15 MbChr 7: 43.3 – 43.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sialic acid-binding Ig-like lectin 7 is aprotein that in humans is encoded by theSIGLEC7gene.[5][6] SIGLEC7 has also been designated asCD328 (cluster of differentiation 328).

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000168995Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000030474Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Nicoll G, Ni J, Liu D, Klenerman P, Munday J, Dubock S, Mattei MG, Crocker PR (Dec 1999)."Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes".J Biol Chem.274 (48):34089–95.doi:10.1074/jbc.274.48.34089.PMID 10567377.
  6. ^"Entrez Gene: SIGLEC7 sialic acid binding Ig-like lectin 7".

Further reading

[edit]
PDB gallery
  • 1nko: Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7
    1nko: Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7
  • 1o7s: HIGH RESOLUTION STRUCTURE OF SIGLEC-7
    1o7s: HIGH RESOLUTION STRUCTURE OF SIGLEC-7
  • 1o7v: HIGH RESOLUTION STRUCTURE OF SIGLEC-7
    1o7v: HIGH RESOLUTION STRUCTURE OF SIGLEC-7
  • 2df3: The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl
    2df3: The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl
  • 2g5r: Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac)
    2g5r: Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac)
  • 2hrl: Siglec-7 in complex with GT1b
    2hrl: Siglec-7 in complex with GT1b

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

1–50
51–100
101–150
151–200
201–250
251–300
301–350


Stub icon

Thismembrane protein–related article is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=SIGLEC7&oldid=1172399654"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp