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Rufloxacin

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Chemical compound
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(August 2014)
Pharmaceutical compound
Rufloxacin
Skeletal formula of rufloxacin
Space-filling model of the rufloxacin molecule
Clinical data
Other names7-Fluoro-6-(4-methylpiperazin-1-yl)-10-oxo-4-thia-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 9-Fluoro-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]thiazino[2,3,4-ij]quinoline-6-carboxylic acid
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC17H18FN3O3S
Molar mass363.41 g·mol−1
3D model (JSmol)
  • CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F
  • InChI=1S/C17H18FN3O3S/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-21(13)9-11(15(10)22)17(23)24/h8-9H,2-7H2,1H3,(H,23,24) ☒N
  • Key:NJCJBUHJQLFDSW-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Rufloxacin is aquinoloneantibiotic.[1] It is sold under the brand names,Ruflox,Monos,Qari,Tebraxin,Uroflox,Uroclar.

See also

[edit]

References

[edit]
  1. ^Rafalsky V, Andreeva I, Rjabkova E (July 2006)."Quinolones for uncomplicated acute cystitis in women".The Cochrane Database of Systematic Reviews.3 (3): CD003597.doi:10.1002/14651858.CD003597.pub2.PMC 7003573.PMID 16856014.
Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)
DHFR inhibitor
Sulfonamides
(DHPS inhibitor)
Short-acting
Intermediate-acting
Long-acting
Other/ungrouped
Combinations
Other DHPS inhibitors
Quinolones
(inhibit bacterial
topoisomerase
and/orDNA gyrase,
thereby inhibiting
DNA replication)
1st generation
Fluoroquinolones
2nd generation
3rd generation
4th generation
Veterinary
Newer non-fluorinated
Related (DG)
Anaerobic DNA
inhibitors
Nitroimidazole derivatives
RNA synthesis
Rifamycins/
RNA polymerase
Lipiarmycins
Stub icon

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