 | |
| Names | |
|---|---|
| IUPAC name N′-Cyclohexyl-N-(4-morpholinophenyl)-7H-purine-2,6-diamine | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChemSpider |
|
| ECHA InfoCard | 100.164.070 |
| MeSH | C484369 |
| UNII | |
| |
| |
| Properties | |
| C21H27N7O | |
| Molar mass | 393.495 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Reversine, or2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group ofPeter G. Schultz, used forstem celldedifferentiation.[1][2]
It also has the potential to selectively induce cell death in cancer cells.[3]
Reversine is known to act as anantagonist of theadenosineA3 receptor. Reversine is a potent inhibitor of the mitotic kinase Mps1[4] and it is widely used to study the process ofchromosome segregation.
