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Inpharmacokinetics, therate of infusion (ordosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drugshould be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective.

Abbreviations include K_in,^[1] K₀,^[2] or R₀.

It can be calculated as thesteady-state concentration in the plasma multiplied by theclearance:

${\displaystyle K_{in}=C_{ss}\cdot CL}$

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