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Pregnane

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Pregnane
Skeletal formula of pregnane
Ball-and-stick model of the pregnane molecule
Names
IUPAC name
5ξ-Pregnane[1]
Systematic IUPAC name
(1S,3aS,3bS,5aΞ,9aS,9bS,11aR)-1-Ethyl-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
  • InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16?,17-,18-,19-,20-,21+/m0/s1 checkY
    Key: JWMFYGXQPXQEEM-WZBAXQLOSA-N checkY
  • InChI=1/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16?,17-,18-,19-,20-,21+/m0/s1
    Key: JWMFYGXQPXQEEM-WZBAXQLOBZ
  • C41CCCC[C@@]1([C@@H]3[C@H]([C@@H]2CC[C@@H]([C@@]2(C)CC3)CC)CC4)C
Properties
C21H36
Molar mass288.511 g/mol
Density0.926 g/ml
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

Pregnane, also known as17β-ethylandrostane or as10β,13β-dimethyl-17β-ethylgonane, is a C21steroid and, indirectly, aparent ofprogesterone. It is a parenthydrocarbon for two series of steroids stemming from5α-pregnane (originallyallopregnane) and5β-pregnane (17β-ethyletiocholane). It has agonane core.

5β-Pregnane is the parent ofpregnanediones,pregnanolones, andpregnanediols, and is found largely inurine as ametabolic product of 5β-pregnanecompounds.

Pregnanes

[edit]
Steroid nomenclature: Pregnanes have carbons 1 through 21.

Pregnanes aresteroid derivatives with carbons present at positions 1 through 21.

Most biologically significant pregnane derivatives fall into one of two groups:pregnenes andpregnadienes. Another class ispregnatrienes.

Pregnenes

[edit]
Main article:Pregnene
Cortisone

Pregnenes have adouble bond. Examples include:

Pregnadienes

[edit]
Main article:Pregnadiene
Cyproterone acetate

Pregnadienes have twodouble bonds. Examples include:

See also

[edit]

References

[edit]
  1. ^International Union of Pure and Applied Chemistry (2014).Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013.The Royal Society of Chemistry. p. 1530.doi:10.1039/9781849733069.ISBN 978-0-85404-182-4.

External links

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Steroid classification
C17
C18
C19
C20
C21
C23
C24
C27
Functional group
Elements removed
Elements replaced


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