 | |
| Names | |
|---|---|
| IUPAC name 2-(1-oxo-1-phenylpropan-2-yl)isoindole-1,3-dione | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
| ECHA InfoCard | 100.199.129 |
| UNII | |
| |
| |
| Properties | |
| C17H13NO3 | |
| Molar mass | 279.295 g·mol−1 |
| Density | 1.304 g/cm3 |
| Melting point | 87 to 88 °C (189 to 190 °F; 360 to 361 K) |
| Boiling point | 447.2 °C (837.0 °F; 720.3 K) |
| Hazards | |
| Flash point | 204.4 °C (399.9 °F; 477.5 K) |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Phthalimidopropiophenone is a chemical intermediate used in the synthesis ofcathinone. It has been found to be sold on the illicit market as acontrolled substance analogue, but little is currently known about its pharmacology or toxicology.[1]
Phthalimidopropiophenone is not an active stimulant, but is believed to be potentially capable of acting as aprodrug for cathinone when ingested, as similar N-substituted cathinone derivatives have been encountered by law enforcement, and were found to form cathinonein vivo by initial hydroxylation of the pyrrolidine ring followed by subsequent dehydrogenation to the corresponding lactam, then by double dealkylation of the pyrrolidine ring to form the primary amine.[2] It is unclear how rapidly or to what extent this metabolic pathway is followed in humans however, and the phthalimido substituted cathinones encountered may have been produced merely as a more stable form for storage than the relatively unstable primary amine cathinone derivatives.
