 | |
| Established | 2009; 17 years ago (2009) |
|---|---|
| Research type | Basic and Applied |
Field of research | Genomics |
| Director | Cynthia Saloma |
| Location | Quezon City,Philippines 14°39′06″N121°04′18″E / 14.65157°N 121.07168°E /14.65157; 121.07168 |
| Affiliations | University of the Philippines Diliman |
| Website | pgc |
| Map | |
  Location in Metro Manila Show map of Metro Manila.svg) Philippine Genome Center (Luzon) Show map of Luzon.svg) Philippine Genome Center (Philippines) Show map of Philippines | |
ThePhilippine Genome Center (PGC) is a multi-disciplinary research facility inQuezon City,Metro Manila,Philippines which specializes ingenomics.
The Philippine Genome Center was established as a collaboration between theUniversity of the Philippines and theDepartment of Science and Technology (DOST).[1] It was first conceptualized in 2009 in response to theSARS outbreak which affected Hong Kong, thedengue outbreaks which affecting the Philippines, and the then-ongoingH1N1 flu pandemic which originated in Mexico. The first grants received by the PGC were for dengue diagnostic testing andH1N1 surveillance.[2] Initially the facility was placed under the jurisdiction of theUniversity of the Philippines (UP) Diliman's Office of the President as per the approval of the UP Board of Regents in its July 31, 2009 meeting.[3]
The PGC was formally launched on November 28, 2011. In the beginning, the center operated virtually. From January 2013 until the opening of its building on September 11, 2019,[4] it was temporarily housed at theNational Institute of Molecular Biology and Biotechnology at UP Diliman
To make DNA sequencing and bioinformatics services accessible to Filipino researchers, the DNA SequencingCore Facility (DSCF) and Core Facility for Bioinformatics (CFB) were established with funding support from the DOST. On February 26, 2016, the UP Board of Regents approved the transfer of management and supervision of the PGC from the university's Office of the President to the Office of the Vice President for Academic Affairs[3]
In 2019, PGC Mindanao[5] and PGC Visayas[6] were established as satellite offices inMindanao andVisayas respectively.
In January 2020, the PGC in collaboration withUP ManilaNational Institutes of Health developed anRT-PCRSARS CoV-2 detection kit.[7]
In April 2020, the Department of Health has set the Philippine Genome Center as the 18th coronavirus testing hub.[8] It was also tasked to conduct genomic sequencing of COVID-19 samples.[9] In July 2021, PGC Mindanao and PGC Visayas was also given the task of detecting new variants with the plan on giving them machines to conduct genome sequencing.[10] In September 2021, the PGC has shifted its focus towards detecting new COVID-19 variants in the country and less focus on conducting RT-PCR tests.[11]
The PGC has two "core facilities"; the Core Facility for Bioinformatics (CFB) and the DNA Sequencing Core Facility (DSCF). Abiobank is planned as PGC's third facility.[12] The two facilities were funded by a₱100 million (US$2.2 million) grant over three years from the Philippine Council for Industry, Energy and Emerging Technology Research and Development (PCIEERD) of theDepartment of Science and Technology.[2]
Opened on September 24, 2013 The DNA Sequencing Core Facility (DSCF) was the first core facility to open. Genomic studies in the field of agriculture, biodiversity, forensics, health, and ethnicity are conducted in the DSCF with the intent to specifically cater to Filipino needs.[12]DNA andgenome sequencing services are provided at the DSCF.[2]
The Core Facility for Bioinformatics (CFB) is a facility that provides genome-scale data generation and analysis to local researchers in the academe, from government institutions and private organizations. It also provides genomic data storage. It is also augmented by anIBMBlue Gene supercomputer which is also used by thePhilippine Atmospheric, Geophysical and Astronomical Services Administration (PAGASA) andProject Nationwide Operational Assessment of Hazards (Project NOAH) for weather forecast and climate change modelling purposes in addition to genomic research use. The CFB was launched on April 14, 2014 while the supercomputer was made operational within the same day.[13]
PGC Mindanao provides various diagnostics and laboratory services to local researchers and laboratories. These services involve sample preparation,Spectrophotometry,Fluorometry,Polymerase Chain Reaction,Electrophoresis,Flow cytometry and various otherbioinformatics and laboratory services.
The advanced equipment ofPGC Mindanao are housed temporarily in the different laboratories of CSM:Biotechnology,Molecular Biology andExtraction Laboratory.[14]
