 | |
| Clinical data | |
|---|---|
| Trade names | Catron, Cavodil |
| Other names | Amphetamine hydrazide;[1] α-Methylphenethylhydrazine; JB-516; α-Methylphenelzine;N-Aminoamphetamine |
| Routes of administration | Oral |
| ATC code |
|
| Legal status | |
| Legal status | |
| Identifiers | |
| |
| CAS Number |
|
| PubChemCID | |
| ChemSpider |
|
| UNII | |
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.000.215 |
| Chemical and physical data | |
| Formula | C9H14N2 |
| Molar mass | 150.225 g·mol−1 |
| |
 N Y (what is this?) (verify) | |
Pheniprazine, formerly sold under the brand namesCatron andCavodil, is anirreversible andnon-selectivemonoamine oxidase inhibitor (MAOI) of thehydrazine group that was used as anantidepressant to treatdepression in the 1960s.[3][4][5][6] It was also used in the treatment ofangina pectoris andschizophrenia.[7][8] Pheniprazine has been largely discontinued due totoxicity concerns such asjaundice,amblyopia, andoptic neuritis.[9][10][11]
Pheniprazine is amonoamine oxidase inhibitor (MAOI).[3]
Amphetamine has been detected as anactive metabolite of pheniprazine in animals.[12] Pheniprazine produces amphetamine- andpsychostimulant-like effects at high doses in animals.[13] The same is true of certain other MAOIs, includingiproniazid,phenelzine,tranylcypromine, andpargyline, but notnialamide.[13][14][15]
Pheniprazine, also known as α-methylphenethylhydrazine,[1] is aphenethylamine,amphetamine, andhydrazinederivative.
It is a closeanalogue ofphenelzine (phenethylhydrazine) andamphetamine (α-methylphenethylamine) and can also be referred to by synonyms including amphetamine hydrazide,[1] α-methylphenelzine, andN-aminoamphetamine.
Metfendrazine (α,N-dimethylphenethylhydrazine;N-methylpheniprazine) is the correspondingmethamphetamine (N-methylamphetamine)analogue.
Pheniprazine is thegeneric name of the drug and itsINNTooltip International Nonproprietary Name andBANTooltip British Approved Name.[3] It is also known by the former developmental code nameJB-516.[3]
Pheniprazine (α-methylphenethylhydrazine; 1-phenyl-2-hydrazinopropane; amphetamine hydrazide) [...]